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Efeito da dieta enriquecida com rutina sobre os parâmetros sanguíneos e biomarcadores oxidativos em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2014-08-14)
Silver catfish, Rhamdia quelen, is one of the most cultivated fish species in southern Brazil. Products destined for improving rearing and production of this species are required due to its importance for aquaculture. ...
Efeito da exposição aguda à fumonisina B1 nas convulsões induzidas por pentilenotetrazol em camundongos
(Universidade Federal de Santa Maria, 2014-07-24)
Mycotoxins are secondary metabolites, produced by fungi species of the genus Aspergillus,
Fusarium, Penicillium and Claviceps. The high incidence of toxicity is by ingestion of
contaminated plant products and by consuming ...
Eficácia da escada analgésica da organização mundial da saúde (OMS) em um modelo de síndrome dolorosa induzida por paclitaxel em ratos
(Universidade Federal de Santa Maria, 2014-04-09)
Paclitaxel use in cancer is limited by a painful syndrome characterized by acute and chronic phases and by the lack of efficacious therapies. Thus, we assessed the efficacy of analgesics used in the World Health Organization ...
Extrato de Bauhinia variegata possui efeito tipo-antidepressivo em camundongos com envolvimento do sistema monoaminérgico
(Universidade Federal de Santa Maria, 2015-04-10)
Depression is a psychiatric disorder that affects 2-15% of the world population. It is a heterogeneous neuropathology, it includes psychological, behavioral and physiological symptoms. Despite having several treatments for ...
Envolvimento do sistema opióide na dependência de estado induzida pela arcaína em ratos
(Universidade Federal de Santa Maria, 2011-03-02)
Arcaine is a competitive antagonist of the polyamine binding site at the NMDA receptor which induces state-dependent recall. However, no study has addressed the involvement of other neurotransmitter/neuromodulators ...
Contribuição do receptor vaniloide na nocicepção induzida pela injeção periférica de poliaminas em camundongos
(Universidade Federal de Santa Maria, 2010-12-02)
Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or AMPA/kainate) and acid-sensitive (ASIC) receptors. In the present ...
Efeitos da N-acetilcisteína sobre o dano oxidativo renal e hepático de ratos diabéticos
(Universidade Federal de Santa Maria, 2010-10-22)
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia, which is related to oxidative stress and plays an important role in the development of other diseases and tissue damage, such as liver and kidney ...
O papel da enzima Na+,K+-ATPase no déficit cognitivo e no efeito profilático induzido pelo exercício físico após o traumatismo crânio-encefálico
(Universidade Federal de Santa Maria, 2009-09-17)
Traumatic Brain Injury (TBI) is the major cause of death or cognitive deficits in industrialized countries. Although studies have indicate that the oxidative stress and functional deficits after TBI are connected events, ...
Caracterização, avaliação antioxidante e citotóxica dos extratos da polpa e da casca de tucumã (Astrocaryum aculeatum)
(Universidade Federal de Santa Maria, 2012-09-24)
The identification of bioactive compounds in Brazilian fruit is extremely important for bioprospecting of natural substances with potential pharmacotherapeutic. Likewise, evaluations of profiles of antioxidant activity and ...
Estudo da relação entre os níveis de indicadores biológicos de exposição ao tolueno e o estresse oxidativo em expostos ocupacionalmente a tintas
(Universidade Federal de Santa Maria, 2010-03-19)
Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals
are among the main chemical constituents ...