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Atividade anticonvulsivante do óleo de peixe
(Universidade Federal de Santa Maria, 2010-08-18)
Methylmalonic acidemias are inherited metabolic disorders characterized by methylmalonate (MMA) accumulation and neurological dysfunction, including seizures. Dietary fatty acids are known as an important energy source and ...
Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Influência farmacogenética da enzima SOD2 na resposta in vitro ao resveratrol de células mononucleares
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...
Frutose-1,6-bisfosfato e N-acetilcisteína atenuam a formação de produtos proteicos de oxidação avançada, uma nova classe de mediadores inflamatórios, in vitro
(Universidade Federal de Santa Maria, 2012-09-19)
The assessment of biomarkers of reactions involving reactive oxygen species have the
potential not only to determine the extent of oxidative damage, but also to predict the
effectiveness of therapeutic strategies aimed ...
Prostaglandina E2 potencializa as convulsões induzidas por metilmalonato
(Universidade Federal de Santa Maria, 2009-11-23)
Methylmalonic acidemias comprehend a group of innate error of the metabolism (EIM)characterized clinically and biochemically for the tissue accumulation of acid methylmalonic (MMA)and neurological dysfunction, including ...
Avaliação da exposição in vivo ao formaldeído sobre parâmetros do estresse oxidativo, inflamação e modificações epigenéticas
(Universidade Federal de Santa Maria, 2020-10-23)
Air quality has been discussed for some time among the scientific community. Air pollution in the external environment and that of the indoor environment have been caused for concern. Volatile organic compounds (VOCs) are ...
Avaliação do papel do receptor para tromboxanos (TP) durante a epileptogênese
(Universidade Federal de Santa Maria, 2020-03-05)
Convulsive status epilepticus (SE) is a medical emergency that can lead to epilepsy, long lasting brain damage and death. It is known that there is a strong link between epilepsy and inflammation. For instance, it has been ...
Avaliação neuropsicológica e dos marcadores inflamatórios nos pacientes com epilepsia
(Universidade Federal de Santa Maria, 2015-08-31)
The epilepsy is a neurological disorder manifested by recurrent unprovoked
seizures, resulting in harmful effects on the patients. Epileptic seizures are generated
from hypersincronic abnormal discharges of neurons, ...
Efeito in vitro do haloperidol e risperidona na ativação inflamatória de macrófagos RAW 264.7
(Universidade Federal de Santa Maria, 2015-04-10)
Introduction: Antipsychotic drugs, such as haloperidol (typical) and risperidone (atypical)
increase the risk of obesity and other endocrine disturbs in psychiatric patients when used in
long term treatments. There is ...