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Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Efeito da casca de jabuticaba (Myrciaria jaboticaba (Vell.) Berg.) sobre estresse oxidativo e resposta inflamatória em modelo de diabetes mellitus tipo 2 em ratos
(Universidade Federal de Santa Maria, 2014-03-14)
Type 2 diabetes mellitus (DM2) is a multifactorial disease mainly characterized by metabolic disorders related to insulin. Hyperglycemia is one of the causes of excessive generation of reactive oxygen species (ROS) leading ...