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Efeito diferencial do diazepam sobre a atividade da enzima Na+,K+-ATPase no hipocampo e córtex entorrinal
(Universidade Federal de Santa Maria, 2016-11-29)
Na+,K+-ATPase is ubiquitously expressed in the plasma membrane of all animal cells where serves as the principal regulator of intracellular ion homeostasis. Na+,K+-ATPase activity is activated by Na+ and K+ and current ...
Efeito da cafeína sobre a consolidação tardia da memória de medo em ratos
(Universidade Federal de Santa Maria, 2016-07-19)
Caffeine, an antagonist of adenosine receptors, is one of the most widely consumed psychostimulant substance in the world. There are contradicting reports about the effect of caffeine on learning and memory. While some ...
A influência do desbalanço superóxido- peróxido de hidrogênio na resposta à quimioterapia de células de câncer colorretal (HT-29): estudo in vitro
(Universidade Federal de Santa Maria, 2016-02-16)
Introduction: manganese dependent superoxide dismutase (SOD2), is an important antioxidant
enzyme, superoxide dismutase to anion produced in mitochondria in hydrogen peroxide, which in turn
is catalyzed by glutathione ...
Avaliação da atividade de três compostos do óleo de melaleuca sobre o Trypanosoma evansi
(Universidade Federal de Santa Maria, 2016-02-15)
This study aimed the evaluation of the trypanocidal activity of terpinen-4-ol, γ-terpinene and α-terpinene against Trypanosoma evansi in vivo and in vitro. The in vitro assay was performed in culture medium of T. evansi, ...
Participação do sistema GABAérgico no mecanismo de ação anestésica dos óleos essenciais de Aloysia triphylla e Cymbopogon flexuosus em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2016-03-21)
This study demonstrated the sedative and anesthetic activity of the essential oil (EO) of Cymbopogon flexuosus in the silver catfish (Rhamdia quelen). The time for induction and recovery of this EO was compared with the ...
Envolvimento das poliaminas no ataque agudo de gota em camundongos
(Universidade Federal de Santa Maria, 2016-02-26)
Gout attack is characterized severe joint pain and inflammation with concomitant accumulation of monosodium urate (MSU) crystals. However, gout and the mechanisms responsible for the acute attacks are poorly understood, ...