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Itens para a visualização no momento 91-100 of 140
Avaliação da capacidade do disseleneto de difenila em reduzir a falência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2013-09-18)
Paracetamol (APAP) is commonly used analgesic and antipyretic, however high doses can induce damage hepatic. The metabolic N-acetyl-p-benzoquinone imine (NAPQI) is responsible for the toxic effects. The accumulation of ...
Estudo da relação entre os níveis de indicadores biológicos de exposição ao tolueno e o estresse oxidativo em expostos ocupacionalmente a tintas
(Universidade Federal de Santa Maria, 2010-03-19)
Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals
are among the main chemical constituents ...
Efeitos de compostos orgânicos de selênio na toxicidade induzida por metilmercúrio: estudos in vitro
(Universidade Federal de Santa Maria, 2014-10-23)
Methylmercury (MeHg) is a known environmental pollutant that affects a variety of cellular functions, and the
oxidative stress is one of the proposed mechanisms to explain its toxicity. Inhibition of selenoenzymes
(Glutathione ...
Avaliação de biomarcadores associados à inflamação e ao estresse oxidativo em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2013-01-28)
Changes in recent decades in morbidity and mortality of prostate cancer (CAP) is
making if a public health problem in several countries, including Brazil. Several studies
provide evidence that inflammatory processes and ...
Caracterização físico-química do mel do bioma pampa brasileiro e estudo do seu potencial antioxidante in vitro e in vivo em modelo de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2014-03-14)
Honey is a complex mixture produced by honey bees from the nectar, which is used by
its sweetening properties, as well as by its human health benefits. The aim of this study was to
characterize, for the first time in ...
Avaliação do fibrinogênio como uma nova fonte para a formação in vitro de produtos proteicos de oxidação avançada
(Universidade Federal de Santa Maria, 2015-07-08)
Oxidative stress is characterized by an imbalance between the production of free radicals, particularly reactive oxygen species (ROS), and the defense capacity of the organism against these species, leading to a progressive ...
Ação neuroprotetora do composto ebselen e do exercício físico em modelos de doença de Alzheimer esporádica em camundongos
(Universidade Federal de Santa Maria, 2019-02-22)
Alzheimer's Disease (AD) is a neurodegenerative disease that reaches about 47 million people
in the world and this prevalence is expected to increase over the next two decades. A range of
evidence has shown that ...
Cisplatina induz um padrão de toxicidade hepatorrenal diferente em ratos neonatos e adultos
(Universidade Federal de Santa Maria, 2018-07-20)
Cisplatin is a widely used chemotherapeutic to treat several types of tumors on both adult and pediatric subjects. Although cisplatin is widely used, its use is associated with serious toxic effects, including nephrotoxicity ...
A ação anti-inflamatória do lítio é influenciada por fatores genéticos, nutricionais e fármacos antidepressivos: estudos in vitro
(Universidade Federal de Santa Maria, 2017-09-01)
Population aging has increased the prevalence of chronic non-communicable diseases, including psychiatric disorders such as depression and bipolar spectrum disorders (BSDs). Evidence suggests that such disorders are ...
Papel do magnésio na prevenção e reversão de distúrbios motores experimentalmente induzidos
(Universidade Federal de Santa Maria, 2014-10-31)
Chronic treatment of psychotic disorders is associated with adverse effects that affect
motor function. Movement disorders include Parkinsonism, akathisia, dystonia and tardive
dyskinesia. Magnesium (Mg) is an essential ...