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Dano ao DNA no diabetes tipo 2 e sua associação com inflamação, estresse oxidativo, disfunção endotelial, resistência à insulina e à ocorrência de complicações crônicas microvasculares
(Universidade Federal de Santa Maria, 2016-03-15)
Several pathophysiological mechanisms are associated with type 2 diabetes mellitus (type 2 DM), such as glucotoxicity, insulin resistance, inflammation, oxidative stress and endothelial dysfunction, which can result in DNA ...
Determinação de HPAs presentes na nutrição parenteral e avaliação da exposição de neonatos através da presença do 1-hidroxipireno na urina
(Universidade Federal de Santa Maria, 2016-10-19)
Carbon black, which has polycyclic aromatic hydrocarbons (PAHs) adsorbed
on its surface, is used in the composition of rubber for pharmaceutical used in
injectable drugs and parenteral formulations such as amino acid ...
Caracterização molecular de Echinococcus spp. em bovinos no Rio Grande do Sul e avaliação in vitro e ex vivo do óleo de Melaleuca alternifolia frente aos protoescóleces de Echinococcus ortleppi
(Universidade Federal de Santa Maria, 2016-03-04)
Cystic echinococcosis (CE) is a zoonotic disease caused by Echinococcus genus. The larval stage (hydatid cyst) of the parasite causes serious public health problems, and affects various species of animals, causing economic ...
Efeito diferencial do diazepam sobre a atividade da enzima Na+,K+-ATPase no hipocampo e córtex entorrinal
(Universidade Federal de Santa Maria, 2016-11-29)
Na+,K+-ATPase is ubiquitously expressed in the plasma membrane of all animal cells where serves as the principal regulator of intracellular ion homeostasis. Na+,K+-ATPase activity is activated by Na+ and K+ and current ...
Estudo etnofarmacológico, fitoquímico e biológico de Poikilacanthus glandulosus (Nees) Ariza
(Universidade Federal de Santa Maria, 2016-08-25)
Poikilacanthus glandulosus is a subshrub distributed in Southeast and South of Brazil, Paraguay, Argentina and Uruguay and belongs to Acathaceae family. The aim of this study was to perform a phytochemical study and ...
Influência do manuseio neonatal sobre parâmetros comportamentais, bioquímicos e moleculares após o uso de drogas psicoestimulantes em ratos
(Universidade Federal de Santa Maria, 2016-09-21)
The abusive use of psychostimulant drugs is a common social problem in countries of different cultures, with increasing and alarming incidence, whose discontinuance of use is associated with anxiety and depression cases. ...
Potencial antiaterogênico da bixina in vivo e in vitro
(Universidade Federal de Santa Maria, 2016-08-25)
Atherosclerosis is a chronic disease characterized by the accumulation of lipids and fibrous elements in the
intima layer of medium and large caliber arteries. Inflammation, oxidative stress as well as low density
lipoprotein ...
Candida parapsilosis: resistência as equinocandinas e a suscetibilidade a antifúngicos isolados e em combinação
(Universidade Federal de Santa Maria, 2016-08-05)
Candida parapsilosis is a yeast fungus that causes a wide spectrum of infections
predominantly in immunocompromised patients and representing a major cause of
infections related to health care. The emergence of resistance ...
Teor de minerais, perfil oxidativo e toxicidade de Nopalea cochenillifera (L.) salm-dick (cactaceae)
(Universidade Federal de Santa Maria, 2016-08-15)
Nopalea cochenillifera (L.) Salm-Dyck occurs from Mexico to Panama and is acclimatized in several countries. It is a shrubby plant that reaches 3-4 m tall, has a cylindrical body and items called cladodes. This species is ...
Extração, identificação e potencialidades farmacêuticas de compostos obtidos da fibra prensada da palma (Elaeis guineensis Jacq.)
(Universidade Federal de Santa Maria, 2016-07-26)
The increase in palm oil demand in the world market generates a greater amount of co-products
resulting from the extraction process. These by-products are being investigated for the presence of
bioactive compounds, since ...