Buscar
Itens para a visualização no momento 1-10 of 18
Validação de método cromatográfico por exclusão molecular para avaliação de interferon-alfa2a e estudos de correlação
(Universidade Federal de Santa Maria, 2010-09-30)
Human interferon-α2a (hIFN-α2a) is a natural protein produced by the cells of the immune system with antiviral, antiproliferative and immunomodulatory properties. A size exclusion liquid chromatography (SE-LC) method was ...
Atividade anticonvulsivante do óleo de peixe
(Universidade Federal de Santa Maria, 2010-08-18)
Methylmalonic acidemias are inherited metabolic disorders characterized by methylmalonate (MMA) accumulation and neurological dysfunction, including seizures. Dietary fatty acids are known as an important energy source and ...
Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Nanopartículas contendo propionato de clobetasol: preparação, caracterização e incorporação em hidrogéis
(Universidade Federal de Santa Maria, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing
clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol
propionate in nanocapsule suspensions. ...
Prospecção in vitro de associações antifúngicas sinérgicas para Fusarium spp
(Universidade Federal de Santa Maria, 2010-03-26)
The genus Fusarium is characterized by hyaline filamentous fungi that cause a wide spectrum of infections predominantly in immunocompromised patients. These fungal infections show high rates of morbidity and mortality and ...
Influência da temperatura na ação do fungo Duddingtonia flagrans utilizado como controle biológico de Haemonchus contortus em ovinos
(Universidade Federal de Santa Maria, 2010-05-28)
In recent years has increased the search for alternative methods to combat
gastrointestinal parasites, and in this context, biological control achieved by the fungus
Duddingtonia flagrans draws attention. In this study, ...
Traxoprodil atenua as convulsões induzidas por pentilenotetrazol
(Universidade Federal de Santa Maria, 2010-09-23)
There is evidence that while polyamines facilitate seizures by positively modulating N-methyl-D-aspartate receptors (NMDAr), selective antagonists of the NR2B-subunit decrease seizures. However, it remains undetermined ...
Efeito do tempo de pinçamento do cordão umbilical sobre a anemia fisiológica de recém-nascidos a termo
(Universidade Federal de Santa Maria, 2010-07-14)
This study verified the effect of late clamping (from 1 to 3 minutes after it is
born) of the umbilical cord on the levels of hemoglobin, hematocrite and ferritine in
children at birth, at three months and at six months ...
Desenvolvimento e validação de metodologia para avaliação de fosfato de sitagliptina
(Universidade Federal de Santa Maria, 2010-04-16)
Sitagliptin Phosphate is an oral anti-hyperglycemic belonging to a new class of
medicine used in type 2 diabetes treatment, the dipeptidyl dipetidase -4 (DPP-4) enzyme
inhibitors. This drug besides being safe and tolerated, ...
Contribuição do receptor vaniloide na nocicepção induzida pela injeção periférica de poliaminas em camundongos
(Universidade Federal de Santa Maria, 2010-12-02)
Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or AMPA/kainate) and acid-sensitive (ASIC) receptors. In the present ...