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Benznidazol livre e nanoestruturado na terapia da Doença de Chagas experimental e seus efeitos sobre biomarcadores do sistema colinérgico e estresse oxidativo
(Universidade Federal de Santa Maria, 2022-01-27)
Chagas disease (CD) is widely distributed in Latin America, caused by Trypanosoma cruzi. The infection promotes an inflammatory process, which triggers several factors of the immune response. The cholinergic system acts ...
Avaliação de indicadores do estresse oxidativo e da atividade da enzima acetilcolinesterase sangüínea em pacientes com diagnóstico de acidente vascular cerebral isquêmico
(Universidade Federal de Santa Maria, 2006-09-29)
In ischemic stroke, damage to the brain is caused by a reduction or complete blockage of blood flow to parts of the brain, resulting in glucose and oxygen deficiency. It is a leading cause of mortality and disability ...
Potenciais efeitos da cafeína sobre parâmetros bioquímicos e inflamatórios em ratos submetidos ao treinamento intervalado de alta intensidade
(Universidade Federal de Santa Maria, 2017-01-31)
Caffeine has been used as ergogenic substance for the purpose of improving athletic performance or attenuating fatigue mechanisms. However, the ergogenic effect of caffeine on high-intensity exercise remains controversial ...
Efeitos da rutina sobre a atividade da aceticolinesterase e sobre o comportamento em ratos expostos ao cádmio
(Universidade Federal de Santa Maria, 2011-09-09)
This study investigated the effect of administration of cadmium (Cd), Rutin (Rut), or both, on lipid peroxidation in different brain structures, memory, anxiety and activity of the enzyme acetylcholinesterase (AChE) (ex ...
Estudo do perfil oxidativo e atividade da enzima acetilcolinesterase em pacientes com leucemia linfoblástica aguda (lla)
(Universidade Federal de Santa Maria, 2008-01-28)
Acute lymphoblastic leukemia (ALL) is the most common cancer found in the pediatric population and is characterized by uncontrolled proliferation and maturation arrest of lymphoid progenitor cells (lymphoblasts) in the ...
Disseleneto de p-metoxi fenila atenua o prejuízo cognitivo e a injúria cerebral em um modelo da doença de Alzheimer em roedores
(Universidade Federal de Santa Maria, 2012-09-17)
Alzheimer s disease (AD) is a progressive neurodegenerative disorder, mainly characterized by memory and intellectual capacity loss. AD is characterized by deposition of amyloid-β peptide, neurofibrillary tangles, ...