This study evaluated the anesthetic efficacy of eugenol and essential oils (EOs) of Aloysia triphylla and Lippia alba on aquaculture, as well as their stress-reducing effect during transport of shrimp and fish. The ...

Depression and chronic pain coexist in several patients and may be modulated by the same neurotransmitter systems. In this context, various studies have demonstrated that antidepressants from the class of the inhibitors ...

Pythiosis is a disease caused by the oomycete Pythium insidiosum that affects horses, cattle, sheep, cats and humans, and occurs in tropical, subtropical and temperate regions. In horses the lesions are characterized by ...

The gout is an extremely painful type of arthritis. Despite the large number of drugs available for its treatment, they usually cause many adverse effects that limit their use. Then, further investigations are necessary ...

Methadone and ketamine have been used in neuropathic pain management, but the benefits of the association of both drugs are uncertain. Aiming to enhance the analgesic efficacy and to reduce the occurrence of adverse-effects, ...

Ocotea puberula (Lauraceae) is a brazilian native tree, known in the South regions as canela guaicá or canela amarela. Its phytochemical composition includes several alkaloids of aporphinic type, some of them with biological ...

Haloperidol is a typical neuroleptic widely used in the treatment of several psychotic disorders and it remains the most prescribed antipsychotic worldwide, due to its high potency and low cost. Despite its good therapeutic ...

Growing evidence has shown that leukotrienes are important contributors in the pathophysiology of several SNC inflammatory diseases where excitotoxicity is involved, including traumatic brain injury, encephalitis, Parkinson's ...

Metabolic syndrome (MetS) is a complex disorder represented by a set of cardiovascular risk factors, including endothelial dysfunction, oxidative stress and inflammation. Syzygium cumini has hypoglycemic, anti-inflammatory, ...

Animal models as reserpine are helpful to understand the pathophysiology of several diseases with involuntary movements, as Parkinson s disease (PD), and to search efficient treatments. The present study tested the effects ...