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O ensino de ciências nos anos iniciais: sinalizando possibilidades de mudanças
(Universidade Federal de Santa Maria, 2012-12-17)
This current study s general idea was to investigate what students from the first
years of school were aware regarding Science and if such conceptions could differ
among teachers and students. After, it was intended to ...
Efeitos do resveratrol, do suco de uva e do vinho tinto nos biomarcadores de estresse oxidativo e na atividade de ectoenzimas em ratos diabéticos
(Universidade Federal de Santa Maria, 2012-11-28)
Diabetes mellitus is a major public health problem throughout the world. The chronic hyperglycemia present in the diabetic state is associated with increase of oxidative stress, which has been appointed to play a central ...
Ação farmacológica do 3-alquinil selenofeno em modelos de convulsão em ratos jovens
(Universidade Federal de Santa Maria, 2012-03-02)
Seizures have important consequences in terms of mortality and quality of life of the affected population, being a risk factor for the development of cognitive and behavioral abnormalities. Considering the promising ...
Avaliação do potencial terapêutico da Valeriana officinalis e do disseleneto de difenila frente à toxicidade induzida por rotenona em Drosophila melanogaster
(Universidade Federal de Santa Maria, 2012-03-02)
Among various antioxidant therapeutic applications, neuroprotective action is highlighted sinceoxidative stress is recognized as one of the events involved in cell damage which occur in most of neurological disorders, ...
Envolvimento de mastócitos em um modelo de dor pós-operatória em camundongos
(Universidade Federal de Santa Maria, 2012-02-28)
Recent studies have indicated that nearly half of all surgical patients present a picture of moderate to severe pain what become important to understand the mechanisms involved postoperative pain to be better treat it. ...
Associação entre o polimorfismo +3954 do gene da interleucina-1 beta, obesidade, LDL-oxidado e seu potencial efeito lipotóxico
(Universidade Federal de Santa Maria, 2012-03-06)
Obesity is a systemic low grade inflammation, that is associated to the increased production of
proinflammatory molecules by adipose tissue. Besides, the adiposity elevated induces cellular
apoptosis and release of a ...
Avaliação de novos compostos sobre a atividade de colinesterases em modelos in silico e in vitro
(Universidade Federal de Santa Maria, 2012-06-04)
The enzyme acetylcholinesterase (EC 3.1.1.7, AChE) is responsible to terminate acetylcholine activity in
the terminal nervous junctions with its effector organs or post-synaptic sites. The activity of this enzyme
could ...
Efeitos farmacológicos do disseleneto de difenila em modelos de toxicidade induzida por organofosforados em ratos
(Universidade Federal de Santa Maria, 2012-08-10)
Pesticides are substances used in agricultural areas and public health programs to control pests and disease vectors. Among pesticides, organophosphates (OPs) are considered the most toxic to vertebrates. Diphenyl diselenide ...
Mecanismos de captação e toxicidade do metilmercúrio: Envolvimento do sistema glutamatérgico e do cálcio em fatias e mitocôndrias de ratos.
(Universidade Federal de Santa Maria, 2012-01-22)
Methylmercury (MeHg) is a highly toxic environmental contaminant that can be accumulated on several tissues, inducing cellular dysfunction on various organs, especially in the central nervous system (CNS). The mechanisms ...
Ratas lactantes e não lactantes diferem quanto à sensibilidade ao HgCl2: efeito protetor do ZnCl2
(Universidade Federal de Santa Maria, 2012-08-17)
Mercury is a divalent metal found in the liquid state at room temperature without biological function. Occupational exposure to this metal occurs mainly in industrial activities and agriculture. Its toxicity seems to be ...