Now showing items 1-5 of 5
Efeito farmacológico do disseleneto de m-trifluormetil-fenila na comorbidade entre dor e depressão em camundongos
(Universidade Federal de Santa Maria, 2015-07-24)
Chronic pain and depression often coexist, and several mechanisms are involved in the pathogenesis of this comorbidity, which confer it resistance to treatment. The serotonergic system is considered a central mechanism in ...
Avaliação do sistema purinérgico e colinérgico em córtex de ratos após hipóxia-isquemia neonatal
(Universidade Federal de Santa Maria, 2013-03-15)
Hypoxia-ischemia (HI) neonatal is a major cause of morbidity and mortality during the perinatal period and it is an important risk factor for the development of a number of human neurological disorders, such as cerebral ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular diseases development risk. However, these changes in hypothyroidism ...
INFLUÊNCIA FARMACOGENÉTICA DA ENZIMA SOD2 NA RESPOSTA IN VITRO AO RESVERATROL DE CÉLULAS MONONUCLEARES
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...
Disseleneto de difenila em modelos de infecção viral causada por herpes simplex vírus dos tipos 1 e 2
(Universidade Federal de Santa Maria, 2017-03-02)
Infectious diseases caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are among the pathologies that most affect the population. The search for new therapeutic alternatives for its treatment becomes relevant ...