Now showing items 1-6 of 6
Estudos dos mecanismos envolvidos na ação antinociceptiva causada pelo disseleneto de difenila em camundongos
(Universidade Federal de Santa Maria, 2007-08-01)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, diphenyl diselenide, a simple ...
Efeito farmacológico do disseleneto de m-trifluormetil-fenila na comorbidade entre dor e depressão em camundongos
(Universidade Federal de Santa Maria, 2015-07-24)
Chronic pain and depression often coexist, and several mechanisms are involved in the pathogenesis of this comorbidity, which confer it resistance to treatment. The serotonergic system is considered a central mechanism in ...
Disseleneto de difenila em modelos de infecção viral causada por herpes simplex vírus dos tipos 1 e 2
(Universidade Federal de Santa Maria, 2017-03-02)
Infectious diseases caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are among the pathologies that most affect the population. The search for new therapeutic alternatives for its treatment becomes relevant ...
Propriedades antinociceptivas e antioxidantes do disseleneto de bis(fenilimidazoselenazolila) em roedores
(Universidade Federal de Santa Maria, 2016-11-07)
The current available drugs for treatment of disorders related to pain and inflammation present several adverse effects, then the investigation for novel molecules are required. It is known that organoselenium compounds ...
Ação neuroprotetora e anti-inflamatória do disseleneto de difenila e exercício de natação em modelo de envelhecimento em ratos
(Universidade Federal de Santa Maria, 2016-01-29)
Aging is a degenerative process that affects virtually all living organisms. The increase in the inflammatory process seems to be one of the main factors that contribute to aging and inflammaging and neuroinflammation in ...
Ação farmacológica do 4,4’-dicloro-difenil disseleneto em modelos de hiperglicemia e obesidade em ratos
(Universidade Federal de Santa Maria, 2017-03-03)
The obesity epidemic is a worldwide public health problem and is considered one of the leading causes of death and disability worldwide. This is because the pathophysiology of this disease is extremely complex and involves ...