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Avaliação do potencial antioxidante e antibacteriano de Anacardium microcarpum e sua toxicidade em diferentes modelos biológicos in vitro
(Universidade Federal de Santa Maria, 2015-09-11)
Oxidative stress reflects an imbalance between the systemic manifestation of reactive species and a biological system s ability to readily detoxify the reactive intermediates or to repair the resulting damage. This condition ...
Avaliação dos efeitos biológicos do (s) (3-feniltelanil propanamida) succinato de dimetila, um novo telúrio aminoácido derivado do ácido aspártico
(Universidade Federal de Santa Maria, 2011-03-25)
Recent studies from our group demonstrated that the (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate compound, a telluroamino acid showed glutathione peroxidase (GPx)-like activity, attesting to its antioxidant ...
Consumo de mel fornece proteção contra alterações motoras e moleculares induzidas por hipóxia/reperfusão em Drosophila melanogaster
(Universidade Federal de Santa Maria, 2017-02-14)
Honey is a complex product produced by honeybees from nectar, being widely used for its sweetening properties, as well as for its benefits to human health. Honey presents anti-inflammatory, hypoglycemic and antioxidant ...
Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Efeitos do disseleneto de difenila sobre o dano oxidativo causado por paracetamol em cérebro de camundongos
(Universidade Federal de Santa Maria, 2012-06-11)
Acetaminophen (APAP) is the analgesic most used in world, in therapeutic doses does not show toxicity, but in elevated doses can cause hepatic damage due the formation of his metabolic toxic N-acetyl-p-benzoquinonimine ...
Caracterização físico-química do mel do bioma pampa brasileiro e estudo do seu potencial antioxidante in vitro e in vivo em modelo de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2014-03-14)
Honey is a complex mixture produced by honey bees from the nectar, which is used by
its sweetening properties, as well as by its human health benefits. The aim of this study was to
characterize, for the first time in ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of
thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular
diseases development risk. However, these changes in hypothyroidism ...
Atividade antioxidante do e-1,1-metiltio-selenofenil-2-pirrolidinona-hepteno: um composto orgânico de selênio com baixa toxicidade
(Universidade Federal de Santa Maria, 2007-04-20)
The objective of this work was to evaluate the antioxidant activity of (E)-1-(1-(methylthio)-1-selenopheny) hept-1-en-2-yl) pyrrolidin-2-one: an organoselenium compound with low toxicity (compound 1). A number of parameters ...
Efeitos dos compostos de selênio e zinco nas lesões gastrointestinais induzidas por etanol em ratos
(Universidade Federal de Santa Maria, 2012-03-30)
Gastric ulcer is a world widespread illness that affectes a great number of people and it is correlated to life style, food intake, alcohol and smoke in association or not to stress behavior. The lesions are in association ...