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Efeitos de dietas hiperglicídicas e hiperlipídicas sobre a peroxidação lipídica e a atividade da enzima deltaaminolevulinato desidratase em camundongos
(Universidade Federal de Santa Maria, 2004-12-01)
Chronic intake of diets containing high proportion of glucose, sucrose or fat
promotes the development of insulin resistance and type 2 Diabetes mellitus.
Furthermore, high levels of glucose can produce permanent chemical ...
Poliaminas modulam a memória nas tarefas de medo condicionado e esquiva inibitória em ratos
(Universidade Federal de Santa Maria, 2004-09-03)
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of ...
Efeitos do disseleneto de difenila na atividade da enzima δ-aminolevulinato desidratase e em parâmetros bioquímicos de ratos com diabetes mellitus tipo 1
(Universidade Federal de Santa Maria, 2004-07-16)
The hyperglycemia and oxidative stress are factors strongly involved on development of many disorders that characterize the Diabetes Mellitus. It is known that some organic and inorganic selenium compounds are potent ...
Sobre a excitotoxicidade induzida por glutamato em retina embrionária de pinto
(Universidade Federal de Santa Maria, 2004-08-20)
Excitotoxicity refers to the neurodegenerative process initiated by excessive activation of receptors for the neurotransmitter glutamate. This process is one of the
most extensively studied processes of neuronal cell death, ...
Efeitos do herbicida clomazone sobre parâmetros metabólicos e antioxidantes em jundiá (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2004-09-10)
The objective of this study was to evaluate the effect of clomazone herbicide on metabolism of silver catfish (Rhamdia quelen). It was measured levels of lactate, protein and glucose (plasma), glycogen, protein and lactate ...
A inibição da enzima δ-aminolevulinato desidratase por monossacarídeos não é mediada pela oxidação de grupos -sh
(Universidade Federal de Santa Maria, 2004-08-18)
Heme pathway enzyme δ-aminolevulinate dehydratase (δ-ALA-D) is a good marker for oxidative stress and metal intoxication. This sulfhydrylic enzyme is inhibited in several oxidative pathologies like lead, mercury and aluminum ...
Derivados pirazolínicos inéditos causam antinocicepção em camundongos no teste da formalina
(Universidade Federal de Santa Maria, 2004-07-29)
The discovery of pyrazole derivatives dates back to 1884, when the German chemist Ludwig Knorr attempted to synthesize quinoline derivatives with antipyretic activity and accidentally obtained antipyrine, a pyrazolinone, ...
Efeito teratogênico do ditelureto de difenila, administrado durante a gestação em ratas e efeito de organocalcogênios sobre a reprodução em ratos machos
(Universidade Federal de Santa Maria, 2004-07-30)
Organochalcogens are important intermediates and the main applied reagents in organic synthesis and in industrial processes, which can increase human exposure risk to these chemicals in the workplace. The effects of single ...
Atividade de novos antifúngicos sobre Candida spp. e Cryptococcus neoformans
(Universidade Federal de Santa Maria, 2004-08-19)
The fungal infections are becoming an important cause of morbidity and mortality in immunocompromised patients. Here we have studied the activity of new antifungal agents as ravuconazole, albaconazole, micafungin as well ...
Efeito agudo e crônico do etanol sobre as enzimas NTPDase, 5'-nucleotidase, acetilcolinesterase, peroxidação lipídica e comportamento em ratos
(Universidade Federal de Santa Maria, 2004-10-15)
Ethanol is one of the most used substance in different societies. This study was
performed in order to clarify the acute and chronic effects of ethanol on biochemical
and behavioral parameters in male Wistar rats. The ...