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Compostos 1,2 e 1,4-dicarboxílicos atuam sobre o sistema glutamatérgico e o comportamento de ratos e camundongos
(Universidade Federal de Santa Maria, 2005-07-27)
Glutamatergic receptors are targets for many L-glutamate structure analogues, which cause neurotoxicity. This study investigated the actions of two dicarboxylic compounds, the first had cyclic framework and rigid structure, ...
Efeitos tóxicos do etanol e sua relação com o estresse oxidativo
(Universidade Federal de Santa Maria, 2005-08-12)
Ethanol is one of the most ingested substances among the different societies. So, it becomes target of several studies that intent to elucidate its mechanisms of toxicity. This study was aimed to better understand the link ...
Avaliação de parâmetros toxicológicos em piavas (Leporinus sp.) Expostas ao zinco e ao cobre
(Universidade Federal de Santa Maria, 2005-08-19)
The aim of this study was to verify the zinc and copper effects, metals frequently found in aquatic ecosystems, on the metabolism of piavas (Leporinus sp.). In this work, it was verified the average lethal concentrations ...
Efeito da diacereína sobre a febre induzida por suspensão de Saccharomyces cerevisiae e por prostaglandina e2 em ratos jovens
(Universidade Federal de Santa Maria, 2005-06-10)
Fever is a systemic response that results of a cascade of events that usually begins with pathogenic infection. Its development represents an important aspect of host defense that is mediated by the central nervous system. ...
Sensibilidade da enzima acetilcolinesterase (e.c. 3.1.1.7) à nicotina in vitro e in vivo
(Universidade Federal de Santa Maria, 2005-08-18)
This work valued the sensibility of the acetylcholinesterase from different sources and brain regions at nicotine in vitro, and the effects of the acute and subchronic exposures at the alkaloid on the brain acetylcholinesterase ...
Quantificação da glutationa reduzida em eritrócitos humanos por cromatografia líquida de alta eficiência-uv: validação e aplicação
(Universidade Federal de Santa Maria, 2005-02-21)
Oxidative stress may be initiated by a decline in the antioxidant defence system or by an overproduction of free radicals leading to an imbalance between oxidants and antioxidants. The most significant alteration in the ...
Perfil lipídico de pacientes ambulatoriais de Salvador do Sul, RS
(Universidade Federal de Santa Maria, 2005)
Avaliação do potencial antinociceptivo e mecanismo de ação do 2-[5-triclorometil-5-hidroxi-3-fenil-4,5-dihidro-1hpirazol- 1-il] 4-(4 bromofenil)- 5 metiltiazol (b50) em camundongos
(Universidade Federal de Santa Maria, 2005-07-21)
Pain is a common symptom in the clinical practice. Therefore, novel analgesic drugs, with more favorable pharmacological properties have been searched. Previous studies from our group showed that the systemic administration ...
Avaliação das alterações comportamentais, eletrencefalográficas e da oxidação protéica induzidas pela injeção intraestriatal de ácido propiônico em ratos.
(Universidade Federal de Santa Maria, 2005-08-05)
Propionic acid (PA) is found in high amounts in tissues of patients with propionic acidemia, an inherited disorder of amino acid and lipid metabolism caused by severe
deficiency of propionil-CoA-carboxylase activity. PA ...
Interação da alcalinidade e densidade de estocagem em juvenis de jundiá Rhamdia quelen (Heptapteridae)
(Universidade Federal de Santa Maria, 2005-08-15)
To evaluate interaction of water alkalinity and stocking density on body ionic levels, survival, growth and behavior of silver catfish, Rhamdia quelen, juveniles, a short-term experiment (96 h) analyzed the effect of three ...