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Atividade antinociceptiva de derivados 5-trifluormetil-4,5-diidro-1h-pirazol-1-carboxiamida em modelos animais de nocicepção aguda e crônica
(Universidade Federal de Santa Maria, 2008-08-06)
To identify the origin of pain and relieve of it is, certainly, important part of the
treatment of any pathology. Unfortunately, nor all pain modalities possess an
adequate treatment at a moment. Many patients do not obtain ...
Avaliação do potencial antinociceptivo de 5- trialometil- 4,5-diidro-1h- pirazol metil ésteres inéditos em camundongos
(Universidade Federal de Santa Maria, 2008-07-11)
Pain is a common symptom in clinical practice and many advances have been observed in order to obtain more effective analgesic molecules with fewer side
effects. The present study evaluated the antinociceptive potential ...
Avaliação do perfil oxidativo e da atividade de ectoenzimas em pacientes com neoplasia intra-epitelial cervical
(Universidade Federal de Santa Maria, 2008-08-22)
Uterine cancers are considered to be one of the most important malignant diseases of the female genital tract, preceded only by breast cancer. The tumor cells may produce oxidative disturbances as well as damage to the ...
Respostas metabólicas e enzimáticas em jundiás, Rhamdia quelen (heptapteridae) e piavas Leporinus obtusidens (anostomidae) expostos a herbicidas utilizados na cultura do arroz
(Universidade Federal de Santa Maria, 2009-01-15)
The effects of the toxic exposure of fish to the herbicides clomazone (isoxazolidinone-Gamit®), quinclorac (quinoline-Facet®) and metsulfuron methyl (sulfonylurea-Ally®), used in rice fields were investigated. Experiments ...
Influência de produtos alimentícios ricos em fibra na biodisponibilidade de cádmio e de metais essenciais
(Universidade Federal de Santa Maria, 2009-12-21)
Dietary fibers can interfere in the bioavailability of mineral elements both negatively and positively. This has been the subject of several researches because there is a great interest in essential minerals; also, some ...
Efeitos protetores do zinco sobre alterações comportamentais e bioquímicas induzidas pelo mercúrio em ratos jovens
(Universidade Federal de Santa Maria, 2009-12-21)
Mercury is a toxic element that induces biochemical, neurological and behavioral changes, which can persist for a long time after the metal exposure. The contamination by mercury continues being a serious problem of public ...
Sistemas purinérgico e colinérgico e perfil oxidativo no encéfalo de roedores: influência do alumínio e de diferentes dietas
(Universidade Federal de Santa Maria, 2008-03-05)
In this study, the effects of Aluminium (Al) and of different diets, both individually and in association, were investigated through the determination of NTPDase, 5 -nucleotidase and acetylcholinesterase (AChE) activities ...
Interaction of organodiselenides with sulphydryl groups at the active sites of some thiol containing proteins - in vitro and in vivo mechanistic studies in mammalian models of diabetes
(Universidade Federal de Santa Maria, 2008-04-02)
The present study sought to compare the in vitro antioxidant potentials of a newly synthesized organodiselenide, dicholesteroyl diselenide (DCDS) and diphenyl diselenide (DPDS) and their possible interactions with some ...
Atividade das ectonucleotidases, colinesterase sérica e perfil oxidativo no diabetes melito tipo 2 e hipertensão em humanos
(Universidade Federal de Santa Maria, 2008-03-05)
The increase in the NTPDase and 5'-nucleotidase enzymatic activities, in patients with diabetes and hypertension, unchained the investigation of the possible mechanisms involved in the alterations in ectonucleotidases ...
Efeitos de dietas hiperglicídicas e hiperlipídicas sobre a peroxidação lipídica e a atividade da enzima deltaaminolevulinato desidratase em camundongos
(Universidade Federal de Santa Maria, 2004-12-01)
Chronic intake of diets containing high proportion of glucose, sucrose or fat
promotes the development of insulin resistance and type 2 Diabetes mellitus.
Furthermore, high levels of glucose can produce permanent chemical ...