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Papel protetor do 2-feniletinil-butilterúrio em modelos de dano cognitivo em camundongos e na apoptose em células humanas
(Universidade Federal de Santa Maria, 2013-03-27)
Memory is considered to be a process that has several stages, including acquisition, consolidation and retrieval.
Memory impairment occurs when important synapses are modified. Alzheimer s disease (DA) is the most
common ...
Avaliação dos marcadores do estresse oxidativo em indivíduos suplementados com ferro e ácido ascórbico
(Universidade Federal de Santa Maria, 2007-02-13)
Iron is an essential nutrient for cellular activities including oxygen transport, electron transfer, and gene regulation. However, iron is potentially toxic via its redox reactions which generate reactive oxygen species ...
Bioquímica e citogenética de jundias (Rhamdia quelen) expostos a diferentes concentrações de tório
(Universidade Federal de Santa Maria, 2007-02-23)
The objective of this study was to evaluate the effect of thorium (Th) on the metabolism of silver catfish (Rhamdia quelen) through biochemical parameters from the muscle tissue (glycogen, glucose, lactate, protein and ...
Efeito da dieta hiperlipídica e da tintura de Valeriana officinalis no modelo crônico de discinesia orofacial induzida por haloperidol em ratos
(Universidade Federal de Santa Maria, 2006-10-30)
Haloperidol-induced orofacial dyskinesia (OD) is a putative animal model of tardive dyskinesia (TD) whose pathophysiology has been related to an increase in dopamine
turnover, reduction in gabaergic neurotransmission and ...
Atividade antioxidante do e-1,1-metiltio-selenofenil-2-pirrolidinona-hepteno: um composto orgânico de selênio com baixa toxicidade
(Universidade Federal de Santa Maria, 2007-04-20)
The objective of this work was to evaluate the antioxidant activity of (E)-1-(1-(methylthio)-1-selenopheny) hept-1-en-2-yl) pyrrolidin-2-one: an organoselenium compound with low toxicity (compound 1). A number of parameters ...
Retinol e carotenóides em pacientes hemodialisados e seus reflexos fisiopatológicos
(Universidade Federal de Santa Maria, 2009-01-20)
Chronic renal failure (CRF) is a slow and gradual decline of renal function and it
constitutes a major public health problem in our country. The haemodialysis treatment is
the standard to which these patients are submitted. ...
Estudo clínico, randomizado, controlado por placebo do efeito da suplementação de guaraná em marcadores bioquímicos associados à aterosclerose
(Universidade Federal de Santa Maria, 2013-10-19)
Guarana (Paullina cupana) is a functional food and previous studies suggest antioxidant,
antiplatelet,antiobesogenic lipid-lowering and modulating activities of the levels
of nitric oxide (ON) effects.The probably effects ...
Potenciais efeitos da cafeína sobre parâmetros bioquímicos e inflamatórios em ratos submetidos ao treinamento intervalado de alta intensidade
(Universidade Federal de Santa Maria, 2017-01-31)
Caffeine has been used as ergogenic substance for the purpose of improving athletic performance or attenuating fatigue mechanisms. However, the ergogenic effect of caffeine on high-intensity exercise remains controversial ...
Envolvimento do receptor TRPA1 na nocicepção e neuroinflamação observada em modelos de esclerose múltipla em camundongos
(Universidade Federal de Santa Maria, 2022-05-03)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS), and neuropathic pain and headache are significant sensory alterations that are difficult to manage in these patients. In the different ...
Efeitos da rutina sobre a atividade da aceticolinesterase e sobre o comportamento em ratos expostos ao cádmio
(Universidade Federal de Santa Maria, 2011-09-09)
This study investigated the effect of administration of cadmium (Cd), Rutin (Rut), or both, on lipid peroxidation in different brain structures, memory, anxiety and activity of the enzyme acetylcholinesterase (AChE) (ex ...