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Itens para a visualização no momento 11-20 of 28
A melhora da consolidação da memória induzida por espermidina envolve a ativação da via PI3K/AKT
(Universidade Federal de Santa Maria, 2020-10-28)
Memory consolidation is a process that depends on specific brain structures, such as the hippocampus, synthesis of new proteins, activation of protein kinases and neurotrophins, such as the brain-derived neurotrophic factor ...
Depressão e prejuízo de memória induzidos pela administração de estreptozotocina em camundongos: efeitos terapêuticos do disseleneto de p-clorodifenila
(Universidade Federal de Santa Maria, 2020-02-20)
Pre-diabetes and diabetes are metabolic diseases of heterogeneous etiopathology including defects in
the secretion and action of insulin, or both, the presence of hyperglycemia, glucose and insulin
intolerance, disorders ...
Efeito neuroprotetor da Berberina na neurotoxicidade induzida por estreptozotocina e lipolissacarídeo em ratos
(Universidade Federal de Santa Maria, 2019-10-29)
Alzheimer's disease (AD) is considered the major cause of dementia and is characterized by changes in the cholinergic and purinergic system, oxidative stress, inflammatory process and metabolic changes that, in turn, are ...
Efeito amnésico da arcaína depende da novidade e do sistema opióide
(Universidade Federal de Santa Maria, 2012-03-01)
Previous exposure to the training context disrupts glutamatergic N-methyl-Daspartate
receptor (NMDAr) antagonist-induced amnesia, indicating that novelty is
necessary for such an amnestic effect. While there are reports ...
Envolvimento do sistema opióide na dependência de estado induzida pela arcaína em ratos
(Universidade Federal de Santa Maria, 2011-03-02)
Arcaine is a competitive antagonist of the polyamine binding site at the NMDA receptor which induces state-dependent recall. However, no study has addressed the involvement of other neurotransmitter/neuromodulators ...
Espermina reverte o dano de memória induzido por lipopolissacarídeo em camundongos
(Universidade Federal de Santa Maria, 2014-08-21)
Neuroinflammation is a neuropathological finding in a number of neurodegenerative diseases. Intraperitoneal injection of lipopolysaccharide (LPS) induces neuroinflammation and memory deficit. Spermine and spermidine are ...
Avaliação dos efeitos de drogas anti-adenosinérgicas e do disseleneto de difenila no prejuízo da memória e estresse oxidativo relacionados ao envelhecimento
(Universidade Federal de Santa Maria, 2012-08-08)
Biological aging is gradual and progressive decline of physical functions that begin in adulthood and ends with death in almost all animals species. One of the most common features of aging is the reduced ability to learn ...
Efeitos do alumínio na diferenciação neural: envolvimento da sinalização purinérgica
(Universidade Federal de Santa Maria, 2020-03-23)
Aluminum (Al) is considered the most abundant metal in enviorment. In this way, all life forms
are susceptible to constant exposure to this element. The trivalent cationic form of Al, Al3+, is
well known for being the ...
Avaliação neuropsicológica e dos marcadores inflamatórios nos pacientes com epilepsia
(Universidade Federal de Santa Maria, 2015-08-31)
The epilepsy is a neurological disorder manifested by recurrent unprovoked
seizures, resulting in harmful effects on the patients. Epileptic seizures are generated
from hypersincronic abnormal discharges of neurons, ...
4,4'-dicloro-difenil disseleneto reverte o déficit de memória induzido pela corticosterona em camundongos
(Universidade Federal de Santa Maria, 2016-02-29)
Chronic stress or even a single serious traumatic experience may have a negative impact on cognitive function. In this sense, organic selenium compounds are molecules that arouse great interest because they have various ...