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Disseleneto de difenila em modelos de infecção viral causada por herpes simplex vírus dos tipos 1 e 2
(Universidade Federal de Santa Maria, 2017-03-02)
Infectious diseases caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are among the pathologies that most affect the population. The search for new therapeutic alternatives for its treatment becomes relevant ...
Propriedades antinociceptivas e antioxidantes do disseleneto de bis(fenilimidazoselenazolila) em roedores
(Universidade Federal de Santa Maria, 2016-11-07)
The current available drugs for treatment of disorders related to pain and inflammation present several adverse effects, then the investigation for novel molecules are required. It is known that organoselenium compounds ...
Efeitos do laser sobre as alterações bioquímicas e morfológicas induzidas por um modelo de lesão cutânea em ratos
(Universidade Federal de Santa Maria, 2015-08-05)
Skin ulcer is a condition that can lead to serious complications, when not treated. Among the resources used to treat skin lesions is the low level laser therapy (LLLT), is extensively studied in the literature, wich could ...
Guanonisa reduz a neurotoxicidade e o déficit motor induzido pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2016-01-29)
Traumatic brain injury (TBI) affects annually 10 million of people causing neurological symptoms and deaths resulting in an adverse socio-economic impact worldwide. The pathophysiology of TBI comprises multiple neurotoxic ...
Potencial antiaterogênico da bixina in vivo e in vitro
(Universidade Federal de Santa Maria, 2016-08-25)
Atherosclerosis is a chronic disease characterized by the accumulation of lipids and fibrous elements in the
intima layer of medium and large caliber arteries. Inflammation, oxidative stress as well as low density
lipoprotein ...
Extrato bruto de Hymenaea courbaril L. apresenta efeito antinociceptivo em modelos de dor em camundongos
(Universidade Federal de Santa Maria, 2016-09-29)
Hymenaea courbaril L. (Fabaceae), popularly known in Brazil as "Jatoba" is a tropical species of South America. Hymenaea genus is commonly used in Brazilian traditional medicine for the treatment of inflammation, bacterial ...
Ação neuroprotetora e anti-inflamatória do disseleneto de difenila e exercício de natação em modelo de envelhecimento em ratos
(Universidade Federal de Santa Maria, 2016-01-29)
Aging is a degenerative process that affects virtually all living organisms. The increase in the inflammatory process seems to be one of the main factors that contribute to aging and inflammaging and neuroinflammation in ...
Influência da suplementação com creatina pós-exercício excêntrico na sinalização miogênica e rendimento físico em ratos
(Universidade Federal de Santa Maria, 2017-09-01)
Creatine (Cr) is one of the most studied compounds in sports in the world due to its proven ergogenic properties. In this context, recent studies have highlighted other effects of Cr, demonstrating a possible trophic effect ...
Ação farmacológica do 4,4’-dicloro-difenil disseleneto em modelos de hiperglicemia e obesidade em ratos
(Universidade Federal de Santa Maria, 2017-03-03)
The obesity epidemic is a worldwide public health problem and is considered one of the leading causes of death and disability worldwide. This is because the pathophysiology of this disease is extremely complex and involves ...
Efeitos da cafeína e do diclofenaco sobre o estresse oxidativo e a inflamação em ratos submetidos ao exercício físico
(Universidade Federal de Santa Maria, 2015-07-01)
Exercise can represent a physical stress that disrupts the homeostasis. Elevated muscle oxygen consumption increases reactive oxygen species (ROS) and inflammatory proteins production, leading to oxidative stress and ...