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Efeitos de diferentes intensidades de exercício resistido em biomarcadores de estresse oxidativo e na atividade das ectonucleotidases em plaquetas de ratos hipertensos
(Universidade Federal de Santa Maria, 2016-01-28)
The objective of this study was to compare and analyze the effects of two 4-week resistance exercise protocols on oxidative stress (OS) biomarkers and ectonucleotidases activities in hypertensive rats. Male Wistar rats ...
Avaliação do potencial antioxidante dos extratos aquoso e etanólico de Mentha pulegium, Uncaria tomentosa e Phyllanthus niruri frente às alterações induzidas por T-butil hidroperóxido em eritrócitos humanos in vitro
(Universidade Federal de Santa Maria, 2016-07-27)
The stone cruscher (Phyllanthus niruri), cat'sclaw (Uncaria tomentosa) and pennyroyal (Mentha pulegium)have been used by people to treat a variety of diseases associated with oxidative stress. In this study, we aimed to ...
Avaliação dos efeitos de uma formulação comercial contendo azadiractina em carpa comum
(Universidade Federal de Santa Maria, 2016-03-10)
Due to the impact caused by synthetic insecticides in the aquatic environment, natural compounds obtained from natural sources have been used in the attempt of minimizing environmental risks. The commercial product NeenMaxTM, ...
Associação do polimorfismo MnSOD ALA16VAL com os biomarcadores inflamatórios, apoptóticos e BDNF em pacientes após acidente vascular encefálico tardio
(Universidade Federal de Santa Maria, 2017-07-01)
Stroke is one of the most frequent neurologic diseases and involves various risk factors such as atherosclerosis, dyslipidemia and diabetes mellitus. Furthermore, the mechanisms of action associated with the pathophysiology ...
Estudo do potencial antioxidante da espécie Caryocar coriaceum Wittm. em modelos experimentais in vitro e in vivo
(Universidade Federal de Santa Maria, 2016-04-29)
Despite the diversity of species found in the National Araripe Forest, Ceará Cariri, there are few studies with Caryocar coriaceumWittm (C. coriaceum), a plant that produces a highly consumed fruit in regional cuisine. The ...
Influência do manuseio neonatal sobre parâmetros comportamentais, bioquímicos e moleculares após o uso de drogas psicoestimulantes em ratos
(Universidade Federal de Santa Maria, 2016-09-21)
The abusive use of psychostimulant drugs is a common social problem in countries of different cultures, with increasing and alarming incidence, whose discontinuance of use is associated with anxiety and depression cases. ...
Disseleneto de difenila em modelos de infecção viral causada por herpes simplex vírus dos tipos 1 e 2
(Universidade Federal de Santa Maria, 2017-03-02)
Infectious diseases caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are among the pathologies that most affect the population. The search for new therapeutic alternatives for its treatment becomes relevant ...
Efeitos da combinação de paracetamol e cafeína sobre a bioenergética mitocondrial em fígado de camundongos
(Universidade Federal de Santa Maria, 2017-07-28)
Paracetamol (acetaminophen, N-acetyl-p-aminofenol, APAP) is a drug with analgesic and antipiretic effects, widely used, presenting low cost, easier aquisition and clinical efficacy. Accidental or intentional use of high ...
Efeito do ácido cafeico e ácido cafeico fenetil éster em modelo de inflamação induzida por lipopolisacarídeo
(Universidade Federal de Santa Maria, 2016-08-05)
Peripheral inflammation is able to cause alterations in central nervous system (CNS) and lead to progression of neurodegenerative diseases. During neuroinflammatory process the activation of immune cells from the CNS and ...
Caenorhabditis elegans como modelo experimental para estudos toxicológicos e farmacológicos dos extratos de Luehea divaricata e Paullinia cupana
(Universidade Federal de Santa Maria, 2016-03-16)
The nematode Caenorhabditis elegans is a valuable tool for toxicological and
pharmacological studies. Despite its simple body, the most part of its genes and signaling
pathways are similar to humans, and alterations in ...