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Piper methysticum altera a atividade locomotora e parâmetros bioquímicos em Drosophila melanogaster
(Universidade Federal de Santa Maria, 2017-02-08)
Piper methysticum (P. methysticum), popularly known as Kava Kava, is used for the treatment of anxiety due to its action on the Central Nervous System (CNS). However, its action mechanism continues being investigated. In ...
Avaliação da sinalização purinérgica em tecido hepático e esplênico de camundongos infectados com Toxoplasma gondii e tratados com disseleneto de difenila
(Universidade Federal de Santa Maria, 2017-02-03)
Toxoplasmosis is a zoonosis of worldwide distribution caused by the parasite Toxoplasma gondii, which in general develops asymptomatic and chronic characteristic infection in mammals and birds. In this period, the parasite ...
Um conto sobre a agressividade: valor de recurso, tomada de decisão e adaptações morfológicas
(Universidade Federal de Santa Maria, 2017-02-15)
Agonistic behavior is ubiquituous in nature. Hence, understanding how and why it occurs is fundamental for unravelling its influence in the evolution of behavior. The goals of this thesis are: to test the influence of ...
Envolvimento dos sistemas purinérgico, colinérgico e estresse oxidativo nos distúrbios da tireoide: possível efeito protetor da quercetina
(Universidade Federal de Santa Maria, 2017-02-22)
Thyroid hormones modulate the metabolic pathways in the body and have important physiological
functions in the brain and vascular system. Changes in their production or distribution lead to disorders
such as hypothyroidism ...
Efeitos do ácido gálico na sinalização purinérgica em linfócitos e plaquetas de ratos submetidos a um modelo experimental de diabetes
(Universidade Federal de Santa Maria, 2017-03-21)
Diabetes mellitus (DM) is a chronic metabolic disease associated with hyperglycemia, systemic inflammatory changes and vascular endothelial dysfunction. NTPDase, 5'-nucleotidase and adenosine deaminase (ADA) are important ...
Efeitos da suplementação com disseleneto de difenila e do exercício físico de natação na memória de ratos wistar velhos
(Universidade Federal de Santa Maria, 2017-03-03)
Aging occurs at all cellular levels of the body, being defined as a degenerative, progressive
and irreversible process. An important feature of the aging process is the gradual loss of
memory. Given the scarcity of ...
Ação farmacológica do 4,4’-dicloro-difenil disseleneto em modelos de hiperglicemia e obesidade em ratos
(Universidade Federal de Santa Maria, 2017-03-03)
The obesity epidemic is a worldwide public health problem and is considered one of the leading causes of death and disability worldwide. This is because the pathophysiology of this disease is extremely complex and involves ...
Helmintofauna de anuros em campo nativo e área de cultivo no sul do Brasil
(Universidade Federal de Santa Maria, 2017-02-17)
The Campos Sulinos are grassy formations where there is high biodiversity, but the conservation of these grasslands has been neglected, while the degradation and the habitat advance at alarming rates. The impacts of habitat ...
Discinesia espontânea em ratos: possível participação de mecanismos oxidativos e dopaminérgicos
(Universidade Federal de Santa Maria, 2017-08-17)
Tardive dyskinesia is a movement disorder that develops as a result of prolonged use of antipsychotics, mainly the typical ones, in approximately 20% to 25% of patients and, as age increases, it afflicts about 50% of ...
Desenvolvimento de nanocápsulas contendo disseleneto de bis (p-metoxifenila): biodistribuição e efeitos em modelos de dor em camundongos
(Universidade Federal de Santa Maria, 2017-08-11)
The chronic pain is a global public health problem and its pharmacological management is still unsatisfactory. The identification of novel molecules to effectively treat chronic pain states remains a major objective in ...