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Traxoprodil atenua as convulsões induzidas por pentilenotetrazol
(Universidade Federal de Santa Maria, 2010-09-23)
There is evidence that while polyamines facilitate seizures by positively modulating N-methyl-D-aspartate receptors (NMDAr), selective antagonists of the NR2B-subunit decrease seizures. However, it remains undetermined ...
Efeito do tempo de pinçamento do cordão umbilical sobre a anemia fisiológica de recém-nascidos a termo
(Universidade Federal de Santa Maria, 2010-07-14)
This study verified the effect of late clamping (from 1 to 3 minutes after it is
born) of the umbilical cord on the levels of hemoglobin, hematocrite and ferritine in
children at birth, at three months and at six months ...
Desenvolvimento e validação de metodologia para avaliação de fosfato de sitagliptina
(Universidade Federal de Santa Maria, 2010-04-16)
Sitagliptin Phosphate is an oral anti-hyperglycemic belonging to a new class of
medicine used in type 2 diabetes treatment, the dipeptidyl dipetidase -4 (DPP-4) enzyme
inhibitors. This drug besides being safe and tolerated, ...
Contribuição do receptor vaniloide na nocicepção induzida pela injeção periférica de poliaminas em camundongos
(Universidade Federal de Santa Maria, 2010-12-02)
Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or AMPA/kainate) and acid-sensitive (ASIC) receptors. In the present ...
Efeitos da N-acetilcisteína sobre o dano oxidativo renal e hepático de ratos diabéticos
(Universidade Federal de Santa Maria, 2010-10-22)
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia, which is related to oxidative stress and plays an important role in the development of other diseases and tissue damage, such as liver and kidney ...
Estudo da relação entre os níveis de indicadores biológicos de exposição ao tolueno e o estresse oxidativo em expostos ocupacionalmente a tintas
(Universidade Federal de Santa Maria, 2010-03-19)
Paints occupational exposure is an important health problem due to the wide variety of chemicals and xenobiotics present in their constitution. Organic solvents and heavy metals
are among the main chemical constituents ...
Eriodictiol: um flavonóide antagonista do receptor TRPV1 com atividade antioxidante
(Universidade Federal de Santa Maria, 2010-08-13)
The transient receptor potential vanilloid 1 (TRPV1) is a calcium permeable channel responsible for the transduction and modulation of acute and chronic pain signaling, being a potential target for treatment of different ...
Creatina aumenta a atividade da Na+,K+-ATPase e previne o aparecimento das convulsões induzidas por pentilenotetrazol em ratos
(Universidade Federal de Santa Maria, 2010-02-26)
Creatine, an endogenous guanidino compound produced on liver, kidneys, pancreas, testes and brain, has been aim of several studies over the last years. Although most studies attribute the effects of creatine to their
energetic ...
Concepções sobre o câncer e o seu tratamento no contexto hospitalar e escolar
(Universidade Federal de Santa Maria, 2010-03-26)
In this study was analysed the conceptions about cancer and its treatment on the educational context under two aspects: in the hospital and at school, though active intervention of the pharmaceutical professional. In the ...
Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...