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Itens para a visualização no momento 201-209 of 209
Influência de diferentes ácidos graxos sobre parâmetros comportamentais e oxidativos em ratos submetidos ao estresse agudo
(Universidade Federal de Santa Maria, 2013-08-30)
The fatty acids (FA) are important constituents of brain phospholipid membranes and play important roles in the central nervous system (CNS) may modify the plasticity and fluidity, and act decisively in the development of ...
Envolvimento do receptor de potencial transitório A1 (TRPA1) em um modelo de dor neuropática mantida pelo simpático em camundongos
(Universidade Federal de Santa Maria, 2012-05-26)
Some forms of neuropathic pain are maintained by sympathetic fibers, but the underlying mechanisms are poorly understood. Thus, the aim of this study was to investigate the possible involvement of the TRPA1 receptor as ...
Hormônio alfa estimulante dos melanócitos (α-MSH) não modifica as convulsões induzidas por pentilenotetrazol e por pilocarpina em camundongos
(Universidade Federal de Santa Maria, 2013-11-26)
Alpha-melanocyte stimulating hormone (α-MSH) is a pro-opiomelanocortin (POMC)-derived peptide involved in different neurological functions that also exerts anti-inflammatory effects, including in the central nervous system ...
Influência de estrógenos e progestinas sobre a atividade da superóxido dismutase e o estatus oxidativo em mulheres
(Universidade Federal de Santa Maria, 2013-05-20)
The deficit of estrogen that accompanies menopause may be involved in the metabolic changes and increased oxidative stress during non-reproductive female life. Hormone replacement therapy (HRT) has been used to attenuate ...
Desenvolvimento e validação de um método automatizado para a quantificação dos níveis séricos de nitrito/nitrato
(Universidade Federal de Santa Maria, 2012-03-09)
Nitric oxide (NO) is a reactive free radical, acting as a messenger molecule, mediating several functions, including vasodilation, platelet aggregation inhibition and neurotransmission. Because this radical to have a short ...
Envolvimento das poliaminas no ataque agudo de gota em camundongos
(Universidade Federal de Santa Maria, 2016-02-26)
Gout attack is characterized severe joint pain and inflammation with concomitant accumulation of monosodium urate (MSU) crystals. However, gout and the mechanisms responsible for the acute attacks are poorly understood, ...
Emprego do óleo de Borago officinalis L. no desenvolvimento de formulações semissólidas e nanocápsulas poliméricas destinadas ao tratamento tópico de doenças inflamatórias da pele
(Universidade Federal de Santa Maria, 2014-04-28)
This study aimed to obtain semisolids formulations and lipid core nanocapsules containing borage oil associated or not with betamethasone dipropionate, for their application in the treatment of atopic dermatitis. A gel-cream ...
Receptores EP1 E EP3 modulam as crises epilépticas induzidas por pentilenotetrazol e ácido caínico em camundongos
(Universidade Federal de Santa Maria, 2013-06-27)
Epilepsy is one of the most common neurologic disorders. It has been suggested that
seizures may be facilitaded by inflammation. PGE2 is one of the most important inflammatory
mediators, and facilitates pentylenetetrazol ...
Propriedades antitumorais do açaí (Euterpe oleracea, Mart., 1824) e avaliação do desbalanço oxidativo relacionado ao genótipo da SOD2 em células saudáveis
(Universidade Federal de Santa Maria, 2019-08-28)
Cancer is one of the main problems of public health worldwide, and in most cases occurs in cells of epithelial origin, since they have a high proliferative rate and have limited characteristics of cell senescence. These ...