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Efeitos anti-nociceptivo e anti-edematogênico da glibenclamida em um modelo de gota aguda em ratos
(Universidade Federal de Santa Maria, 2013-02-23)
Gout is one form of inflammatory arthritis, which is caused by the precipitation of crystals of monosodium urate (MSU) in the joints. Acute gout is associated with sudden and painful inflammatory episodes characterized by ...
Compostos 1,2 e 1,4-dicarboxílicos atuam sobre o sistema glutamatérgico e o comportamento de ratos e camundongos
(Universidade Federal de Santa Maria, 2005-07-27)
Glutamatergic receptors are targets for many L-glutamate structure analogues, which cause neurotoxicity. This study investigated the actions of two dicarboxylic compounds, the first had cyclic framework and rigid structure, ...
Mecanismos de captação e toxicidade do metilmercúrio: Envolvimento do sistema glutamatérgico e do cálcio em fatias e mitocôndrias de ratos.
(Universidade Federal de Santa Maria, 2012-01-22)
Methylmercury (MeHg) is a highly toxic environmental contaminant that can be accumulated on several tissues, inducing cellular dysfunction on various organs, especially in the central nervous system (CNS). The mechanisms ...
Poliaminas modulam a memória nas tarefas de medo condicionado e esquiva inibitória em ratos
(Universidade Federal de Santa Maria, 2004-09-03)
The polyamines, spermine, spermidine and putrescine, are a group of aliphatic amines that interact with diverse cellular targets such as nucleic acids and proteins. The polyamines may act as physiological modulators of ...
Efeitos tóxicos do etanol e sua relação com o estresse oxidativo
(Universidade Federal de Santa Maria, 2005-08-12)
Ethanol is one of the most ingested substances among the different societies. So, it becomes target of several studies that intent to elucidate its mechanisms of toxicity. This study was aimed to better understand the link ...
Efeitos do disseleneto de difenila na atividade da enzima δ-aminolevulinato desidratase e em parâmetros bioquímicos de ratos com diabetes mellitus tipo 1
(Universidade Federal de Santa Maria, 2004-07-16)
The hyperglycemia and oxidative stress are factors strongly involved on development of many disorders that characterize the Diabetes Mellitus. It is known that some organic and inorganic selenium compounds are potent ...
Avaliação de parâmetros toxicológicos em piavas (Leporinus sp.) Expostas ao zinco e ao cobre
(Universidade Federal de Santa Maria, 2005-08-19)
The aim of this study was to verify the zinc and copper effects, metals frequently found in aquatic ecosystems, on the metabolism of piavas (Leporinus sp.). In this work, it was verified the average lethal concentrations ...
Efeito da diacereína sobre a febre induzida por suspensão de Saccharomyces cerevisiae e por prostaglandina e2 em ratos jovens
(Universidade Federal de Santa Maria, 2005-06-10)
Fever is a systemic response that results of a cascade of events that usually begins with pathogenic infection. Its development represents an important aspect of host defense that is mediated by the central nervous system. ...
Trichoderma e bradyrhizobium no desenvolvimento e produtividade da soja
(Universidade Federal de Santa Maria, 2018-05-14)
Soy is a very important crop and for success in cultivation, many factors are critical and help increase productivity. One of these factors is the seed treatment, since it aims to ensure the protection of seeds in the soil. ...
A influência de gradientes ambientais e da radiação ultravioleta sobre comunidades de anuros do extremo sul da Mata Atlântica
(Universidade Federal de Santa Maria, 2017-02-16)
Amphibians are among the most threatened vertebrate groups on the planet, mainly due
to anthropic activity and the side effects of these activities. Thus, in the present work we
evaluated how the modification of the ...