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Efeitos comportamentais e endócrinos da exposição na fase embrionária ao etonogestrel em peixe-zebra
(Universidade Federal de Santa Maria, 2023-09-18)
Improper disposal of expired drugs directly into the garbage or sewage systems
without specific treatment increases concentration of these components in wastewater.
Waste from pharmaceutical industries, used in research ...
Prescrição de fármacos inapropriados em idosos hospitalizados: análise da mortalidade e sobrevida
(Universidade Federal de Santa Maria, 2023-09-29)
Introduction: Elderly people (>60 years old) have a high prevalence of chronic noncommunicable diseases (DCNTs), often managed through the daily use of four or more
drugs (polypharmacy). Furthermore, they may present ...
Avaliação da influência da dieta em parâmetros de estresse oxidativo, inflamação e modificações epigenéticas em pacientes com lúpus eritematoso sistêmico
(Universidade Federal de Santa Maria, 2023-10-11)
Exacerbated cellular activation due to autoimmunity in Systemic Lupus Erythematosus (SLE)
can generate an imbalance between antioxidants and pro-oxidants, triggering oxidative stress.
In addition to oxidative stress, ...
Consequências da exposição ao levonorgestrel em zebrafish: efeitos persistentes e transgeracionais
(Universidade Federal de Santa Maria, 2023-09-18)
The consumption of contraceptive medications such as levonorgestrel (LNG) has
increased considerably in recent decades, and consequently its disposal in the
environment, and it has already been detected in different ...
Emprego do óleo de Borago officinalis L. no desenvolvimento de formulações semissólidas e nanocápsulas poliméricas destinadas ao tratamento tópico de doenças inflamatórias da pele
(Universidade Federal de Santa Maria, 2014-04-28)
This study aimed to obtain semisolids formulations and lipid core nanocapsules containing borage oil associated or not with betamethasone dipropionate, for their application in the treatment of atopic dermatitis. A gel-cream ...
Influência da dose de cetamina e da pioglitazona em sintomas tipo-esquizofrenia e marcadores bioquímicos em camundongos
(Universidade Federal de Santa Maria, 2023-10-31)
Schizophrenia is a severe mental illness characterized by positive, negative and cognitive symptoms, whose etiology is not fully elucidated, being cognitive symptoms difficult to treat. Ketamine is a non-competitive NMDA ...
Efeitos do R-(+)-limoneno na dieta sobre o crescimento, metabolismo, estresse e respostas antioxidantes de peixes infectados ou não com Aeromonas hydrophila
(Universidade Federal de Santa Maria, 2023-12-12)
Intensive fish farming can lead to stressful situations that affect their growth. Aeromonas
hydrophila is a challenging pathogen for the productive success of fish. In addition to causing
outbreaks with mass death of ...
Receptores EP1 E EP3 modulam as crises epilépticas induzidas por pentilenotetrazol e ácido caínico em camundongos
(Universidade Federal de Santa Maria, 2013-06-27)
Epilepsy is one of the most common neurologic disorders. It has been suggested that
seizures may be facilitaded by inflammation. PGE2 is one of the most important inflammatory
mediators, and facilitates pentylenetetrazol ...
Propriedades antitumorais do açaí (Euterpe oleracea, Mart., 1824) e avaliação do desbalanço oxidativo relacionado ao genótipo da SOD2 em células saudáveis
(Universidade Federal de Santa Maria, 2019-08-28)
Cancer is one of the main problems of public health worldwide, and in most cases occurs in cells of epithelial origin, since they have a high proliferative rate and have limited characteristics of cell senescence. These ...
Perfil redox, imunológico e histopatológico de jundiás infectados por Aeromonas hydrophila e tratados com extrato de folhas de Hesperozygis ringens (Benth.) Epling
(Universidade Federal de Santa Maria, 2024-01-30)
Aquaculture represents an essential practice for feeding the growing world population and has demonstrated record expansion levels. Combined with this growth, bacterial outbreaks have emerged and lead to large losses in ...