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Atividade antimicrobiana, sinérgica e antibiofilme de sildenafil frente a Pseudomonas aeruginosa
(Universidade Federal de Santa Maria, 2021-03-29)
The increase in antimicrobial resistance has made the therapeutic armamentarium against bacterial infections increasingly scarce, generating a serious public health problem, especially in the hospital environment. In this ...
Morfoanatomia, controle físico-químico e atividade anti-inflamatória de Blepharocalyx salicifolius (Kunth) O. Berg. (Myrtaceae)
(Universidade Federal de Santa Maria, 2011-12-23)
The implantation of the quality control in the different stages of development and production, since the collection until the end item is of vital importance to guarantee the security and the consumed vegetal product ...
Atividade antimicrobiana do óleo essencial de Gaultheria procumbens: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2022-08-14)
The pharmacological study of medicinal plants has been highlighted by the identification of
new substances. Plant secondary metabolites are substances produced in response to stress,
often related to attacks by herbivores, ...
Avaliação de metodologia para análises in silico de dados de sequenciamento de genoma total de Klebsiella pneumoniae resistente a carbapenêmicos
(Universidade Federal de Santa Maria, 2021-10-14)
The emergence of Klebsiella pneumoniae strains resistant to different antimicrobial classes has
increased the concern regarding control and monitoring measures for this microorganism.
Whole Genome Sequencing (WGS) has ...
Revisão sistemática e metanálise do efeito analgésico do ácido alfa-lipóico em estudos clínicos e atividade antinociceptiva em um modelo de SDCR tipo I
(Universidade Federal de Santa Maria, 2023-02-10)
Chronic pain is a common type of disabling pain, which may or may not be related to other pathologies. It is known that oxidative stress generates compounds that activate ion channels, which are related to increased pain ...
Perfil clínico, oxidativo e inflamatório em pacientes com SARS-CoV-2
(Universidade Federal de Santa Maria, 2023-02-28)
In December 2019, cases of serious illness that caused an outbreak of pneumonia of unknown
origin were reported in Wuhan, Hubei Province, China. Soon after, the number of cases
skyrocketed dramatically, spreading across ...
Fotoinativação de micobactérias de crescimento rápido por porfirinas tetra-catiônicas
(Universidade Federal de Santa Maria, 2023-01-23)
Antimicrobial Photodynamic Inactivation (aPDI) is an emerging non-invasive treatment that
involves the use of a photosensitizer (PS), light and molecular oxygen to inactivate
microorganisms. Thus, the application of aPDI ...
Monitoramento terapêutico e farmacocinética populacional da amicacina administrada em pacientes internados no Hospital Universitário de Santa Maria
(Universidade Federal de Santa Maria, 2022-09-13)
Serious infections in a hospital environment, especially in critically ill patients, continue to be a significant problem for the health systems associated with high morbidity and mortality rates. Amikacin is an important ...
Análise de modificações proteicas induzidas in vitro sobre a formação de produtos proteicos de oxidação avançada e a quantificação de proteína C-reativa
(Universidade Federal de Santa Maria, 2023-02-24)
Non-enzymatic protein modification reactions occur physiologically and affect many
proteins. In some situations, such as kidney and inflammatory diseases, these
reactions are exacerbated. The consequences of these ...
Hemodiálise: controle de infeção, qualidade microbiológica do líquido de diálise versus reuso de dialisadores
(Universidade Federal de Santa Maria, 2023-01-25)
Introduction: The high incidence of complications originating from venous accesses has
stimulated the development of research based on the environment were hemodialysis sessions.
In this context, the microbiological ...