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Efeitos da suplementação com disseleneto de difenila e do exercício físico de natação na memória de ratos wistar velhos
(Universidade Federal de Santa Maria, 2017-03-03)
Aging occurs at all cellular levels of the body, being defined as a degenerative, progressive
and irreversible process. An important feature of the aging process is the gradual loss of
memory. Given the scarcity of ...
Dieta suplementada com disseleneto de difenila atenua as alterações bioquímicas e comportamentais no modelo de hipotireoidismo induzido por metimazol
(Universidade Federal de Santa Maria, 2012-12-14)
Hypothyroidism is a syndrome resulting from decreased production and secretion of triiothyronine (T3) and thyroxine (T4) hormones, frequently diagnosed in women. Clinical and experimental evidence support the association ...
Efeitos da dieta contendo disseleneto de difenila sobre respostas comportamentais, bioquímicas e moleculares em um modelo de hiperglicemia em peixe-zebra
(Universidade Federal de Santa Maria, 2018-08-06)
Studies have been demonstrating an increasing number of secondary complications caused by diabetes. Among them are neuropsychiatric diseases such as anxiety and depression. In addition, oxidative stress is known to play a ...
Efeito do disseleneto de difenila sobre alterações comportamentais e bioquímicas induzidas por anfetamina em camundongos
(Universidade Federal de Santa Maria, 2012-09-19)
Selenium is an element that can modulate the dopaminergic neurotransmission.
Studies show that diphenyl diselenide, an organic compound of selenium, has
antioxidant activity improves depressive-like behavior and reduce ...
Os efeitos de organocalcogêneos e de 2,3-dimercaptopropanol sobre convulsão química e letalidade induzidas por pentilenotetrazol e 4-aminopiridina em camundongos
(Universidade Federal de Santa Maria, 2007-08-17)
Experimental models of seizure in animals have represented an important role for the understanding of the physiological and behavioural alterations associated with the human epilepsy. The induction of partial or generalized ...
Avaliação da capacidade do disseleneto de difenila em reduzir a falência hepática aguda induzida por paracetamol em camundongos
(Universidade Federal de Santa Maria, 2013-09-18)
Paracetamol (APAP) is commonly used analgesic and antipyretic, however high doses can induce damage hepatic. The metabolic N-acetyl-p-benzoquinone imine (NAPQI) is responsible for the toxic effects. The accumulation of ...
Avaliação do efeito do disseleneto de difenila na nocicepção induzida pela administração neonatal de glutamato monossódico em ratos
(Universidade Federal de Santa Maria, 2014-09-09)
Monosodium glutamate (MSG) has been the target of research due to its toxicological effects. Neonatal administration of MSG in animals can affect the morphological and electrophysiological organization of the brain, leading ...
Avaliação do desgaste promovido pela broca post preparation utilizando imagens de TCCB
(Universidade Federal de Santa Maria, 2005-01-03)
Several metals are known to disturb cellular functions by binding to thiol groups of biomolecules. Therefore, a possible therapy for metal intoxication is to remove the toxic metals from the bound functional bioligands by ...
Atividade hipolipidêmica do disseleneto de difenila na hiperlipidemia induzida por Triton WR-1339 em camundongos
(Universidade Federal de Santa Maria, 2009-11-26)
In mammals, the liver plays a central role in whole-body lipid metabolism. Unfortunately, dysregulation of these pathways has been implicated in hyperlipidemias. In recent years, a significant association between the trace ...
Efeito do tipo antidepressivo do disseleneto de difenila em um modelo de depressão induzida por malation em ratos
(Universidade Federal de Santa Maria, 2010-04-01)
Organophosphorus (OP), among them malathion, are responsible for most of the poisonings reported annually in Brazil. In addition to symptoms of cholinergic
poisoning, the exposure to OP causes affective and cognitive ...