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Itens para a visualização no momento 11-20 of 35
Efeitos da VD3 sobre a memória e sobre o sistema purinérgico e colinérgico em um modelo de demência esporádica do tipo Alzheimer em ratos
(Universidade Federal de Santa Maria, 2014-06-13)
Alzheimer's disease (AD) is considered the main cause of dementia in elderly people worldwide. This disease affects the central nervous system (CNS), especially the cerebral cortex and hippocampus, areas that are responsible ...
A melhora da consolidação da memória induzida por espermidina envolve a ativação da via PI3K/AKT
(Universidade Federal de Santa Maria, 2020-10-28)
Memory consolidation is a process that depends on specific brain structures, such as the hippocampus, synthesis of new proteins, activation of protein kinases and neurotrophins, such as the brain-derived neurotrophic factor ...
Depressão e prejuízo de memória induzidos pela administração de estreptozotocina em camundongos: efeitos terapêuticos do disseleneto de p-clorodifenila
(Universidade Federal de Santa Maria, 2020-02-20)
Pre-diabetes and diabetes are metabolic diseases of heterogeneous etiopathology including defects in
the secretion and action of insulin, or both, the presence of hyperglycemia, glucose and insulin
intolerance, disorders ...
Efeito neuroprotetor da Berberina na neurotoxicidade induzida por estreptozotocina e lipolissacarídeo em ratos
(Universidade Federal de Santa Maria, 2019-10-29)
Alzheimer's disease (AD) is considered the major cause of dementia and is characterized by changes in the cholinergic and purinergic system, oxidative stress, inflammatory process and metabolic changes that, in turn, are ...
Efeito amnésico da arcaína depende da novidade e do sistema opióide
(Universidade Federal de Santa Maria, 2012-03-01)
Previous exposure to the training context disrupts glutamatergic N-methyl-Daspartate
receptor (NMDAr) antagonist-induced amnesia, indicating that novelty is
necessary for such an amnestic effect. While there are reports ...
Envolvimento do sistema opióide na dependência de estado induzida pela arcaína em ratos
(Universidade Federal de Santa Maria, 2011-03-02)
Arcaine is a competitive antagonist of the polyamine binding site at the NMDA receptor which induces state-dependent recall. However, no study has addressed the involvement of other neurotransmitter/neuromodulators ...
Efeito neuroprotetor do exercício de natação e do disseleneto de m-trifluormetil difenila em um modelo de dieta hipercalórica em camundongos jovens
(Universidade Federal de Santa Maria, 2021-05-21)
The nutrition transition process has generated negative impacts on population health. The increasing consumption of foods and beverages with higher energy density and lower nutritional value promotes damage to the body, ...
Espermina reverte o dano de memória induzido por lipopolissacarídeo em camundongos
(Universidade Federal de Santa Maria, 2014-08-21)
Neuroinflammation is a neuropathological finding in a number of neurodegenerative diseases. Intraperitoneal injection of lipopolysaccharide (LPS) induces neuroinflammation and memory deficit. Spermine and spermidine are ...
Avaliação dos efeitos de drogas anti-adenosinérgicas e do disseleneto de difenila no prejuízo da memória e estresse oxidativo relacionados ao envelhecimento
(Universidade Federal de Santa Maria, 2012-08-08)
Biological aging is gradual and progressive decline of physical functions that begin in adulthood and ends with death in almost all animals species. One of the most common features of aging is the reduced ability to learn ...
Efeitos do alumínio na diferenciação neural: envolvimento da sinalização purinérgica
(Universidade Federal de Santa Maria, 2020-03-23)
Aluminum (Al) is considered the most abundant metal in enviorment. In this way, all life forms
are susceptible to constant exposure to this element. The trivalent cationic form of Al, Al3+, is
well known for being the ...