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Itens para a visualização no momento 11-20 of 28
Efeito da (+)-catequina sobre adiscinesia orofacial induzida por reserpina em camundongos e atividade damonoaminoxidase
(Universidade Federal de Santa Maria, 2018-03-20)
Tardive dyskinesia (TD) is a disabling and debilitating disorder due to the chronic use of antipsychotics that affects around 20% to 50% of patients. It is characterized by involuntary, repetitive and abnormal movements ...
Neuroproteção do cassis (Ribes nigrum L.) e de sua associação com o Donepezil em modelo de amnésia induzida por escopolamina
(Universidade Federal de Santa Maria, 2019-12-13)
Memory deficits that occur with the process of aging could also be associated with the pathophysiology of neurodegenerative diseases, such as Alzheimer’s disease (AD). AD is characterized by the progressive deterioration ...
Avaliação da capacidade antioxidante in vitro de novos compostos mono e disseleneto
(Universidade Federal de Santa Maria, 2013-07-26)
The antioxidant action of organic selenium compounds, as well as ebselen and diphenyl diselenide (DPDS), is closely connected to its ability of generating the selenol group. (In) this study it was evaluated the in vitro ...
Estudo das propriedades antioxidantes de diferentes ftalocianinas
(Universidade Federal de Santa Maria, 2013-02-22)
Oxidative stress is believed to be involved in the etiology of several chronic diseases, including cardiovascular disease, diabetes, cancer, and neurodegenerative disorders. From this perspective, we have evaluated the ...
Efeito protetor do extrato hidroalcoólico de própolis marrom nas lesões vaginais induzidas pelo herpes simples vírus tipo 2
(Universidade Federal de Santa Maria, 2013-01-25)
Propolis is a natural compound and has been highlighted for its antioxidant, antiinflammatory
and antiviral properties. The purpose of this study was to investigate if
brown hydroalcoholic propolis extract (HPE) protects ...
Síntese e atividades antioxidante e antitumoral de 5´-arilseleno azidotimidina
(Universidade Federal de Santa Maria, 2012-03-30)
The synthesis of compounds that use a nucleoside as the base structure, has an intense field application. Among these compounds, the most known nowadays is azydothymidine or zidovudine, a drug which was first synthesized ...
Efeito antioxidante de uma nova classe de compostos teluroacetilenos: estudos in vitro e in vivo
(Universidade Federal de Santa Maria, 2010-04-01)
Organotellurium compounds have been reported as antioxidants in several models of oxidative stress, especially in the brain. This study investigated the effect of telluroacetylenes a-d on pharmacological assays in vitro. ...
Efeito do Harpagophytum procumbens sobre parâmetros de estresse oxidativo e a viabilidade celular in vitro
(Universidade Federal de Santa Maria, 2013-10-04)
Harpagophytum procumbens, known as devil's claw, is an African plant with numerous therapeutic effects, among which stands out for its powerful anti-inflammatory action, but the mechanism by which exerts its effect is not ...
Efeitos do disseleneto de difenila sobre o dano oxidativo causado por paracetamol em cérebro de camundongos
(Universidade Federal de Santa Maria, 2012-06-11)
Acetaminophen (APAP) is the analgesic most used in world, in therapeutic doses does not show toxicity, but in elevated doses can cause hepatic damage due the formation of his metabolic toxic N-acetyl-p-benzoquinonimine ...
Caracterização físico-química do mel do bioma pampa brasileiro e estudo do seu potencial antioxidante in vitro e in vivo em modelo de Drosophila melanogaster
(Universidade Federal de Santa Maria, 2014-03-14)
Honey is a complex mixture produced by honey bees from the nectar, which is used by
its sweetening properties, as well as by its human health benefits. The aim of this study was to
characterize, for the first time in ...