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Efeitos do consumo de ácidos graxos n-3, n-6 e trans sobre aspectos bioquímicos e moleculares em um modelo animal de mania
(Universidade Federal de Santa Maria, 2014-07-18)
Fatty acids (FA) are constituents of neuronal phospholipid membranes, where they are essential for the development and functioning of the brain. During the peak of neuronal growth, occurring during the last week of gestation ...
Ação protetora do licopeno sobre as alterações induzidas pela micotoxina zearalenona em camundongos machos
(Universidade Federal de Santa Maria, 2014-12-22)
Zearalenone (ZEA) an estrogenic mycotoxin and, therefore the reproductive system as one of its main targets of toxicity. Besides being a mycotoxin and toxigenic immunosuppressive, the ZEA hematological changes and promotes ...
Contribuições para o uso de células estromais mesenquimais no reparo de feridas cutâneas e no transplante de pele em coelhos
(Universidade Federal de Santa Maria, 2014-03-14)
This thesis was carried out in three distinct stages; the first being intended to analyzing the cell therapy of skin wound healing in rabbits. The aim of this work was to evaluate the healing potential of the stromal ...
Atividade de ectoenzimas do sistema purinérgico e análise de biomarcadores inflamatórios e de estresse oxidativo em pacientes com câncer de pulmão
(Universidade Federal de Santa Maria, 2014-11-13)
Lung cancer has been considered a public health problem since it has become one of the most commonly diagnosed neoplastic diseases and one of the most lethal in the world. This spread of lung cancer in the world population ...
Efeitos metabólicos do consumo da castanha do Brasil (Bertholletia excelsa) em humanos saudáveis
(Universidade Federal de Santa Maria, 2014-02-25)
Brazil nut (Bertholletia excelsa, Lecythidaceae family) is the richest known food in selenium. Its consumption has demonstrated efficient in improving the lipid profile and the plasmatic selenium levels as well as to ...
Atividade da curcumina livre e nanoencapsulada in vitro e in vivo sobre ratos infectados experimentalmente com Trypanosoma evansi
(Universidade Federal de Santa Maria, 2014-02-25)
The aim of this study was to evaluate the in vitro and in vivo trypanocidal activity of free curcumin (F-C) and curcumin-loaded lipid-core nanocapsules (C-LNCs) against Trypanosoma evansi, as well as its antioxidant activity ...
Efeito protetor do exercício físico nas alterações bioquímicas e cognitivas iniciais e tardias induzidas pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2014-08-23)
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in industrialized countries leading to the motor and cognitive deficits. Evidence demonstrated that exercise is neuroprotective in traumatic brain ...
Efeitos do consumo de sacarose sobre parâmetros metabólicos, desenvolvimentais e antioxidantes em Drosophila melanogaster: papel das plantas Syzygium cumini e Bauhinia forficata
(Universidade Federal de Santa Maria, 2014-03-14)
The fruit fly, Drosophila melanogaster, has been considered a suitable model organism for investigation of developmental/metabolic dysfunctions and therapeutic strategies. In this work Drosophila melanogaster larvae were ...
Efeitos da oxima butano-2,3-dionatiossemicarbazona frente ao dano testicular causado por cádmio em camundongos
(Universidade Federal de Santa Maria, 2014-03-06)
We investigated the action of butane-2,3-dione thiosemicarbazone oxime against the testicular damage caused by cadmium chloride (CdCl2) in mice swiss adult male. The animals received a single injection of CdCl2 at the dose ...
Influência da suplementação de diferentes ácidos graxos sobre o fotodano da pele induzido pela exposição de roedores à radiação ultravioleta
(Universidade Federal de Santa Maria, 2014-02-18)
Diet fatty acids (FA) are fundamental to the phospholipids structure and function of cell membranes, in which long chain polyunsaturated FA (PUFA) increase its fluidity, while the trans FA (TFA) to make it more rigid. Also, ...