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Atividade anticonvulsivante do óleo de peixe
(Universidade Federal de Santa Maria, 2010-08-18)
Methylmalonic acidemias are inherited metabolic disorders characterized by methylmalonate (MMA) accumulation and neurological dysfunction, including seizures. Dietary fatty acids are known as an important energy source and ...
Estudo do potencial analgésico e antiinflamatório do 3-(4-fluorfenil)-5-trifluormetil-1h-1-tosilpirazol em modelos de dor em camundongos
(Universidade Federal de Santa Maria, 2009-12-18)
Pain is the most common complaint in the medical field and the identification of compounds that can effectively treat painful states without induction of side-effects remains a major challenge in biomedical research. The ...
Efeitos do laser sobre as alterações bioquímicas e morfológicas induzidas por um modelo de lesão cutânea em ratos
(Universidade Federal de Santa Maria, 2015-08-05)
Skin ulcer is a condition that can lead to serious complications, when not treated. Among the resources used to treat skin lesions is the low level laser therapy (LLLT), is extensively studied in the literature, wich could ...
Guanonisa reduz a neurotoxicidade e o déficit motor induzido pelo traumatismo cranioencefálico em ratos
(Universidade Federal de Santa Maria, 2016-01-29)
Traumatic brain injury (TBI) affects annually 10 million of people causing neurological symptoms and deaths resulting in an adverse socio-economic impact worldwide. The pathophysiology of TBI comprises multiple neurotoxic ...
Extrato bruto de Hymenaea courbaril L. apresenta efeito antinociceptivo em modelos de dor em camundongos
(Universidade Federal de Santa Maria, 2016-09-29)
Hymenaea courbaril L. (Fabaceae), popularly known in Brazil as "Jatoba" is a tropical species of South America. Hymenaea genus is commonly used in Brazilian traditional medicine for the treatment of inflammation, bacterial ...
Influência da suplementação com creatina pós-exercício excêntrico na sinalização miogênica e rendimento físico em ratos
(Universidade Federal de Santa Maria, 2017-09-01)
Creatine (Cr) is one of the most studied compounds in sports in the world due to its proven ergogenic properties. In this context, recent studies have highlighted other effects of Cr, demonstrating a possible trophic effect ...
Efeitos da oxima butano-2,3-dionatiossemicarbazona frente ao dano testicular causado por cádmio em camundongos
(Universidade Federal de Santa Maria, 2014-03-06)
We investigated the action of butane-2,3-dione thiosemicarbazone oxime against the testicular damage caused by cadmium chloride (CdCl2) in mice swiss adult male. The animals received a single injection of CdCl2 at the dose ...
Efeito anti-inflamatório do ácido cafeico sobre o sistema purinérgico e colinérgico em ratos Diabéticos tipo 1
(Universidade Federal de Santa Maria, 2020-02-27)
Diabetes mellitus (DM) is a metabolic disorder, considered one of the biggest public health problems in the world. This disease is characterized by a state of chronic hyperglycemia that leads to metabolic disorders. Studies ...
Oleorresina de copaíba apresenta atividade antinociceptiva tópica em um modelo de queimadura de pele induzido por radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2020-11-27)
Burn injuries are common worldwide, representing a major public health problem responsible for more than 180,000 deaths annually. These injuries can be caused by several factors, including ultraviolet (UV) radiation. ...
Influência farmacogenética da enzima SOD2 na resposta in vitro ao resveratrol de células mononucleares
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...