Widespread and prolonged usage of azoles in recent years has led to the rapid development of drug resistance in Candida species. In Candida albicans, resistance to fluconazole causes cross-resistance to other antifungals ...

Fibrates constitute an important class of drugs used in the treatment of the dyslipidemia, which is the main risk factor for the aterosclerosis development and incidence of cardiovascular diseases. The present dissertation ...

The Scrophulariaceae family is composed of some 25 genera and more than 1200 species. The genus Buddleja, widely distributed around the world, belongs to this family presently. Buddleja thyrsoides Lam. species, object ...

In this work, six triazene compounds are assayed to DNA cleavage activity. The same six triazenes and the drug Asercit® (dacarbazine) are assayed to antibacterial activity and toxicity to Artemia salina Leach.: ...

The fexofenadina is an antihistamine non sedative that acts as antagonistic selective in the outlying receivers H1 of the histamine, being used in the symptomatic treatment of allergic manifestations as medication of first ...

In recent years, the isolation of bacteria producing β-lactamases has caused concern around the world, due to the fact these enzymes hydrolysis the ring β-lactam antimicrobials used in the main clinic. This aim of this ...

The aim of the present study was to evaluate the stability of the active principal ingredient of carvedilol, and the release of the drug in vitro, through studies of dissolution. In the stability study were used hydrolytic ...

Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by the disease world-wide, and anemia is a common finding in patients with CKD. Anemia impacts negatively on cardiovascular ...

Conyza bonariensis (L.) is a native plant of South America, easily found in the south area. It s popular name is buva or margaridinha-do-campo. This plant is very used in folk medicine for rheumatism, gout, cystitis, ...

The genus Senecio (Asteraceae) constitutes a group of cosmopolitan plants formed by more than 2000 species. Although most of these plants are considered to be toxic due to the presence of pyrrolizidine alkaloids, several ...