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Now showing items 11-20 of 326
Ditelureto de difenila induz prejuízos no desenvolvimento, neurotoxicidade e desmielinização no sistema nervoso central de filhotes de ratos wistar
(Universidade Federal de Santa Maria, 2009-11-20)
The purpose of this study was to investigate if myelinogenesis is related to the mechanism by which diphenyl ditelluride [(PhTe)2] causes toxicity in rat pups. The present study was performed to examine whether the behavioral ...
Efeito in vitro do polimorfismo ala16val do gene da superóxido dismutase dependente de manganês no metabolismo oxidativo de linfócitos
(Universidade Federal de Santa Maria, 2010-03-05)
Epidemiological studies suggest that the imbalance in antioxidant enzymes activity genetically caused, increases the risk of metabolic disorders and chronic noncommunicable
diseases. This is the case of polymorphism that ...
Efeitos do mercúrio sobre a atividade das enzimas alanina aminotransferase, lactato desidrogenase e glicose 6-fosfatase de ratos jovens
(Universidade Federal de Santa Maria, 2010-03-25)
Mercury is an environmental contaminant, and may accumulate in living organisms causing several damage. Studies have shown that this metal causes several physiological and biochemical alterations in young rats which are ...
Agentes poliaminérgicos modulam a extinção do medo condicionado contextual em ratos
(Universidade Federal de Santa Maria, 2009-11-23)
Polyamines, such as spermidine and spermine, have been reported to improve memory retention through the activation of N-methyl-D-aspartate receptors (NMDAr).
However whether polyamine agonists and antagonists alter extinction ...
Sobre a excitotoxicidade induzida por glutamato em retina embrionária de pinto
(Universidade Federal de Santa Maria, 2004-08-20)
Excitotoxicity refers to the neurodegenerative process initiated by excessive activation of receptors for the neurotransmitter glutamate. This process is one of the
most extensively studied processes of neuronal cell death, ...
Efeitos do herbicida clomazone sobre parâmetros metabólicos e antioxidantes em jundiá (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2004-09-10)
The objective of this study was to evaluate the effect of clomazone herbicide on metabolism of silver catfish (Rhamdia quelen). It was measured levels of lactate, protein and glucose (plasma), glycogen, protein and lactate ...
Sensibilidade da enzima acetilcolinesterase (e.c. 3.1.1.7) à nicotina in vitro e in vivo
(Universidade Federal de Santa Maria, 2005-08-18)
This work valued the sensibility of the acetylcholinesterase from different sources and brain regions at nicotine in vitro, and the effects of the acute and subchronic exposures at the alkaloid on the brain acetylcholinesterase ...
A inibição da enzima δ-aminolevulinato desidratase por monossacarídeos não é mediada pela oxidação de grupos -sh
(Universidade Federal de Santa Maria, 2004-08-18)
Heme pathway enzyme δ-aminolevulinate dehydratase (δ-ALA-D) is a good marker for oxidative stress and metal intoxication. This sulfhydrylic enzyme is inhibited in several oxidative pathologies like lead, mercury and aluminum ...
Quantificação da glutationa reduzida em eritrócitos humanos por cromatografia líquida de alta eficiência-uv: validação e aplicação
(Universidade Federal de Santa Maria, 2005-02-21)
Oxidative stress may be initiated by a decline in the antioxidant defence system or by an overproduction of free radicals leading to an imbalance between oxidants and antioxidants. The most significant alteration in the ...
Derivados pirazolínicos inéditos causam antinocicepção em camundongos no teste da formalina
(Universidade Federal de Santa Maria, 2004-07-29)
The discovery of pyrazole derivatives dates back to 1884, when the German chemist Ludwig Knorr attempted to synthesize quinoline derivatives with antipyretic activity and accidentally obtained antipyrine, a pyrazolinone, ...