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Mecanismos de toxicidade de Duguetia furfuraceae A. St.-Hill no modelo de Drosophila melanogaster e avaliação do potencial antifúngico.
(Universidade Federal de Santa Maria, 2015-12-04)
Duguetia furfuracea is a common shrub from Brazilian cerrado areas, known as "ata brava", often used as a medicinal plant especially in treatment of renal colic and rheumatism. However, pharmacological studies with extracts ...
Respostas bioquímicas em carpas (Cyprinus carpio) expostas a duas formulações comerciais de inseticidas em condições de lavoura de arroz e em laboratório
(Universidade Federal de Santa Maria, 2012-07-27)
The pesticides are substances widely used in agriculture, because it enhances productivity. However, its excessive and disordered use has caused different impacts on the environment. Therefore, this study investigated the ...
Papel da vitamina D3 em doenças neurológicas e avaliação pré-clinica na demência esporádica do tipo Alzheimer
(Universidade Federal de Santa Maria, 2019-09-06)
Dementia is a brain disorder characterized by decline of some function, resulting in deficits in memory functioning and in dialy cognitive tasks. Evidence has emerged that Vitamin D3 (VD3) has innumerable functions in the ...
Efeito neuroprotetor da Berberina na neurotoxicidade induzida por estreptozotocina e lipolissacarídeo em ratos
(Universidade Federal de Santa Maria, 2019-10-29)
Alzheimer's disease (AD) is considered the major cause of dementia and is characterized by changes in the cholinergic and purinergic system, oxidative stress, inflammatory process and metabolic changes that, in turn, are ...
Silimarina modifica a atividade da Na+/K+-ATPase e da MAO e modula a ação de antimicrobianos in vitro
(Universidade Federal de Santa Maria, 2015-06-10)
The Silymarin is a flavonolignan complex isolated from milk thistle seeds of Silybum marianum being used in the treatment of injury related to oxidative stress, including liver and neurological diseases, as Parkinson ...
Efeitos de compostos orgânicos de selênio frente à toxicidade induzida por glutamato e metilmercúrio
(Universidade Federal de Santa Maria, 2012-03-02)
Organoselenium compounds have been proposed as potential pharmacological agents in the treatment of diseases associated with the oxidative stress. Particularly, ebselen and diphenyl diselenide has been demonstrated as ...
Efeitos da N-acetilcisteína sobre a toxicidade do ditelureto de difenila no encéfalo de camundongos
(Universidade Federal de Santa Maria, 2015-11-18)
The diphenyl ditelluride (PhTe)2 is one of the most toxic organic compounds of tellurium which can make their use unsafe. The mechanism(s) involved in (PhTe)2 toxicity is(are) elusive, but thiol oxidation of critical ...
Envolvimento do receptor de potencial transitório anquirina 1 e efeito farmacológico da diosmetina na queimadura de pele induzida pela radiação UVB em camundongos
(Universidade Federal de Santa Maria, 2021-05-11)
Excessive exposure to type B ultraviolet radiation (UVB) can lead to several changes to the skin resulting from the oxidative and inflammatory processes installed through the neuronal and non-neuronal receptors activation. ...
Efeito neuroprotetor do exercício de natação e do disseleneto de m-trifluormetil difenila em um modelo de dieta hipercalórica em camundongos jovens
(Universidade Federal de Santa Maria, 2021-05-21)
The nutrition transition process has generated negative impacts on population health. The increasing consumption of foods and beverages with higher energy density and lower nutritional value promotes damage to the body, ...
Estudo do perfil oxidativo e avaliação de parâmetros enzimáticos em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2012-12-19)
Prostate cancer is recognized as one of the most important medical problems in
the male population. Inherent or acquired alterations in cellular metabolism that occur
over the years may be involved in the process of ...