Secreção de irisina em diferentes intensidades de exercício físico em mulheres com obesidade

Abstract

The drastic increase in overweight and obesity in the world is frightening and there are several causes. About two billion adults worldwide are overweight, with 500 million considered obese. In Brazil, around 20% of the population is obese and 60% of Brazilian adults are overweight, twice as many as 30 years ago. In 2012, the hormone called Irisin was discovered, which seems to be related to obesity and to many of the beneficial effects provided by regular physical exercise. Although exercise has been shown to be effective in increasing the concentration of plasmatic irisin, the relationship between exercise intensity and its secretion in obese women is still unclear. Therefore, the aim of this study is to evaluate the circulating irisin response after an acute aerobic exercise session at different intensities in obese women. This is an experimental study in which the study group was composed of six women with obesity grades I and II (experimental group) from the endocrinology outpatient clinic of the University Hospital of Santa Maria (HUSM) and five eutrophic women (control group). All participants had their blood pressure, heart rate and serum irisin levels assessed before and after a session of low- and high-intensity physical exercise. The study showed that in obese women, low-intensity exercise causes a decrease in circulating levels of irisin while high-intensity physical exercise causes a slight increase. In the group of eutrophic women, high-intensity exercise caused a decrease in circulating irisin levels and low-intensity exercise, an increase. It is concluded that the level of body fat may be an intervening factor in the secretion of irisin during different intensities of physical exercise.