Buscar
Itens para a visualização no momento 1-10 of 18
Neurotoxidade Neonatal do Metilmalonato é suficiente para iniciar déficit de memória em camundongos: envolvimento de marcadores inflamatórios e apoptóticos
(Universidade Federal de Santa Maria, 2014-06-28)
The methylmalonic acidemia is an inborn error of metabolism (IEM) characterized by methylmalonic acid (MMA) accumulation in body fluids and tissues, causing neurological dysfunction, mitochondrial failure, oxidative stress ...
O uso do eugenol contra Aeromonas hydrophila e seu efeito sobre parâmetros hematológicos e imunológicos em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2014-02-25)
In aquaculture, eugenol have been used and recommended as anesthetics for several fish
species. Moreover, this product has attracted the attention of researchers because of its
chemopreventive, anti-inflammatory and ...
Diazepam e fluoxetina inibem a resposta de estresse em zebrafish (Danio rerio)
(Universidade Federal de Santa Maria, 2014-08-27)
The presence of pharmaceuticals in the aquatic environment has long been reported for some years in various studies. However, the impact of drugs on organisms present in aquatic ecosystems is still poorly known. Thus, we ...
Influência farmacogenética da enzima SOD2 na resposta in vitro ao resveratrol de células mononucleares
(Universidade Federal de Santa Maria, 2014-10-03)
Resveratrol (RES) is an anti-aging molecule that provides both anti-inflammatory and antioxidant properties. However, it is unclear whether the basal oxidative state of the cell has any influence on the effects of this ...
Efeito cito-genômico do peróxido de hidrogênio e do guaraná (Paullinia cupana) em células tronco mesenquimais
(Universidade Federal de Santa Maria, 2014-01-22)
With advances in techniques of cell culture, stem cells (SCs) have to be used as an alternative therapy, firming the called regenerative medicine. An type of SC that has been studied is the Adipose-derived stem cell (ASCs) ...
Efeito da administração oral de aflatoxina B1 nas convulsões induzidas em ratos
(Universidade Federal de Santa Maria, 2014-08-14)
Aflatoxins are produced by Aspergillus flavus fungi, mainly A. parasiticus and A. nomius. Aflatoxin B1 (AFB1) is the most common and highly toxic mycotoxin, presents carcinogenic, mutagenic and teratogenic effects. This ...
Efeito in vitro da suplementação do guaraná (Paullinia cupana) na atividade de quimioterápicos usados no tratamento do câncer de mama
(Universidade Federal de Santa Maria, 2014-01-24)
Cancer related fatigue (CRF) is a common phenomenon in patients undergoing chemotherapy and radiotherapy representing a negative impact on functional status and quality of life. Some plants present tonic and antifatiguing ...
Efeito farmacogenético e farmacogenômico do metotrexato na citotoxicidade de células mononucleares periféricas do sangue
(Universidade Federal de Santa Maria, 2014-07-18)
Methotrexate (MTX) is an antimetabolite drug analogue of folic acid with wide clinical application, used in high doses for the treatment of cancer and in low doses for the treatment of autoimmune diseases such as rheumatoid ...
Efeito de dose única de vitamina D nas concentrações séricas de citocinas em mulheres idosas na pós-menopausa
(Universidade Federal de Santa Maria, 2014-03-07)
Vitamin D is an important immunomodulator. Epidemiological studies have shown that vitamin D deficiency impairs the immune functions and participates in the pathogenesis of infectious and autoimmune diseases. Vitamin D ...
Efeito da dieta enriquecida com rutina sobre os parâmetros sanguíneos e biomarcadores oxidativos em jundiás (Rhamdia quelen)
(Universidade Federal de Santa Maria, 2014-08-14)
Silver catfish, Rhamdia quelen, is one of the most cultivated fish species in southern Brazil. Products destined for improving rearing and production of this species are required due to its importance for aquaculture. ...