Fator V de Lendey: um estudo de caso

Abstract

The endurance to the C act ivat ed prot ein together wit h t he Layden’ s V factor mut at ion (FVL) is the most usual genet ic reason of ve ined t hrombos is and it is found in over 20 to 60% of the pat ient wit h thrombophi l ia. In the cases of V factor gene mut at ion the C protein can not be jo ined to broke V factor los ing, t hus, it s r egulator role. Consequent ly, it leads to an increase on clot t ing and thrombin format ion increas ing the chances of thrombus appearance. the present ar t icle approaches t he case of a pat ient wit h chronic thromboembol ism due to the Layden’s V factor mut at ion.