Adenocarcinoma papilar ovariano em um canino: uma abordagem citopatológica

Abstract

Ovarian neoplasms are uncommon in companion animals, corresponding to less than 0.3% of dog neoplasms and about 1% of cats. Usually these tumors are epithelial, being that they most frequently affect animals aged 8 to 12 years old and the highest incidence is observed in females of the Boxer, German Shepherd and Yorkshire Terrier breeds. The exact etiology of the neoplasm has not yet been elucidated, but induction by the administration of diethylstilbestrol for long periods has been described. This paper describes a case of ovarian papillary adenocarcinoma diagnosed using mass cytolopathology in the abdominal cavity of a canine, in the municipality of Santa Maria (RS). The animal was taken to the University Veterinary Hospital of the Federal University of Santa Maria with a history of abdominal volume increase and dyspnea. Complementary tests were requested, which included blood count and biochemicals, ultrasound examination and fine needle cytology (FNC). The clinical-pathological changes were characterized by normochromic normocytic anemia and neutrophilic leukocytosis with a left shift, with no changes in biochemical tests. On ultrasonography, it was possible to observe a large area of irregular contour that extended through the abdomen and nodular structure in the right ovary. Tumor FNC was performed by ultrasound and suggested ovarian papillary adenocarcinoma, confirmed later by histopathology. The animal was submitted to ovariohysterectomy and intravenous chemotherapy with carboplatin. The patient died after undergoing the second chemotherapy session. There are few studies in the literature that describe the use of cytopathology as a diagnostic aid for canine ovarian papillary adenocarcinoma. In this context, coupled with the low frequency of the neoplasia in question, this report demonstrates the importance of cytopathology as a screening tool and aid to diagnosis in the clinic of small animals, which may contribute to the immediate initiation of the therapeutic protocol and / or assistance for a surgical approach to be performed.