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Controle botânico, físico-químico e atividade anti-inflamatória de Glechon spathulata Benth. (Lamiaceae)
(Universidade Federal de Santa Maria, 2010-07-13)
The quality of plant-derived drugs must be ensured through tests of authenticity (organoleptic features,
macro and microscopic identification), purity and integrity (foreign matter, total ash, acid insoluble ash, loss ...
Suscetibilidade de isolados de Candida dubliniensis sensíveis e resistentes ao fluconazol frente a azólicos e equinocandinas
(Universidade Federal de Santa Maria, 2014-06-10)
Candida spp. is the most common etiologic agent of opportunistic fungal infections and Candida albicans species still remains the most frequently isolated species in candidiasis. However, the rate of Candida non-albicans ...
Desenvolvimento e validação de método cromatográfico para avaliação de potência de eritropoietina humana recombinante. Correlação com o ensaio biológico
(Universidade Federal de Santa Maria, 2007-04-10)
Erythropoietin is a glycoprotein which stimulates the erythropoiesis, clinically used for the treatment of renal anaemia. The biological and chromatographic methods for the potency evaluation of recombinant human erythropoietin ...
Atividade de enzimas que degradam nucleotídeos e nucleosídeo da adenina em linfócitos de gestantes soropositivas para toxoplasmose
(Universidade Federal de Santa Maria, 2013-06-26)
Toxoplasmosis, caused by the intracellular protozoan Toxoplasma gondii is an infectious disease, and this triggers the activation of the immune system. The pregnancy, in turn, shows characteristics of systemic inflammatory ...
Hidrogéis de goma de alfarroba contendo compostos indólicos nanoencapsulados com ação anti-inflamatória em desordens cutâneas induzidas em camundongos
(Universidade Federal de Santa Maria, 2019-03-29)
The skin is constantly exposed to external stimuli, such as irritants substances and ultraviolet
radiation type B (UVB), which can trigger an inflammatory response. Indole-3-carbinol (I3C)
and 3-3'-diindolmethane (DIM) ...
Desenvolvimento de suspensões de nanocápsulas para administração sublingual do nifedipino
(Universidade Federal de Santa Maria, 2022-03-14)
Nifedipine is a calcium channel blocker drug used in clinical practice in the treatment of cardiovascular diseases, angina and hypertension. However, nifedipine is photo unstable, has a short biological half-life, low ...
Estudo da caracterização fitoquímica, atividade antioxidante e painel microbiológico do composto bioativo da Rhamnus purshiana (cáscara sagrada) em modelo in vitro
(Universidade Federal de Santa Maria, 2022-06-30)
It is known that about 150 thousand years ago man already used medicinal plants to treat ills
and health problems. The “in natura” consumption of plants or even in the form of derived
products is directly linked to adverse ...
Padronização da quantificação de violaceína produzida por Chromobacterium violaceum através de métodos colorimétricos
(Universidade Federal de Santa Maria, 2022-03-09)
The Quorum Sensing (QS) regulation is closely related to the biofilm formation mechanism in several microrganisms. In the Chromobacterium violaceum (CV) species it is possible to verify this regulation through the production ...
Buddleja thyrsoides Lam.: estudo morfoanatômico, fitoquímico e biológico
(Universidade Federal de Santa Maria, 2007-12-19)
The Scrophulariaceae family is composed of some 25 genera and more than 1200 species.
The genus Buddleja, widely distributed around the world, belongs to this family presently.
Buddleja thyrsoides Lam. species, object ...
Perfil fitoquímico e avaliação dos principais efeitos biológicos e imunológicos In Vitro da Euphorbia tirucalli L.
(Universidade Federal de Santa Maria, 2007-12-12)
Today we can easily find the most diverse kind of information about a particular medicinal plant, but
without scientific basis, making their use a potential risk to health. Overall, the findings on the safety and
efficacy ...