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Desenvolvimento de nanocápsulas contendo cetoprofeno e avaliação in vitro da citotoxicidade
(Universidade Federal de Santa Maria, 2013-08-28)
The aim of this work was to prepare, characterize and evaluate the in vitro cytotoxicity of Eudragit S100® nanocapsules (NC) containing ketoprofen. The nanostructured suspensions were prepared in triplicate by the method ...
Desenvolvimento de nanocápsulas poliméricas para liberação pulmonar do dipropionato de beclometasona
(Universidade Federal de Santa Maria, 2013-03-22)
Polymeric nanocapsules have been studied extensively for drug delivery by various routes of administration. Currently, the nanoencapsulation of drugs is considered the most efficient means of ensuring controlled release, ...
Desenvolvimento tecnológico de produtos secos redispersíveis a partir de nanoestruturas contendo tioconazol
(Universidade Federal de Santa Maria, 2013-04-29)
Spray-drying and freeze-drying are dehydration techniques which serve as alternative to increase the stability of formulations which are in aqueous medium. Therefore, this study objectived the development of redispersible ...
Desenvolvimento tecnológico de suspensões e liofilizados de nanocápsulas poliméricas para a veiculação do neuroprotetor idebenona
(Universidade Federal de Santa Maria, 2013-10-30)
Idebenone is an antioxidant, a synthetic derivative of coenzyme Q10, with several applications, such as neuroprotection. However, this drug has low solubility in water, besides is irritant substance and has chemical ...
Desenvolvimento de nanoemulsões e nanocápsulas poliméricas contendo tioconazol e incorporação em hidrogéis
(Universidade Federal de Santa Maria, 2013-06-21)
This work aimed to develop nanoemulsions and polymeric nanocapsules containing tioconazole for the topical treatment of superficial mycoses. Initially, a method was validated by liquid chromatography with UV detection to ...