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Validação de método cromatográfico por exclusão molecular para avaliação de interferon-alfa2a e estudos de correlação
(Universidade Federal de Santa Maria, 2010-09-30)
Human interferon-α2a (hIFN-α2a) is a natural protein produced by the cells of the immune system with antiviral, antiproliferative and immunomodulatory properties. A size exclusion liquid chromatography (SE-LC) method was ...
Nanopartículas contendo propionato de clobetasol: preparação, caracterização e incorporação em hidrogéis
(Universidade Federal de Santa Maria, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing
clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol
propionate in nanocapsule suspensions. ...
Prospecção in vitro de associações antifúngicas sinérgicas para Fusarium spp
(Universidade Federal de Santa Maria, 2010-03-26)
The genus Fusarium is characterized by hyaline filamentous fungi that cause a wide spectrum of infections predominantly in immunocompromised patients. These fungal infections show high rates of morbidity and mortality and ...
Efeito do tempo de pinçamento do cordão umbilical sobre a anemia fisiológica de recém-nascidos a termo
(Universidade Federal de Santa Maria, 2010-07-14)
This study verified the effect of late clamping (from 1 to 3 minutes after it is
born) of the umbilical cord on the levels of hemoglobin, hematocrite and ferritine in
children at birth, at three months and at six months ...
Desenvolvimento e validação de metodologia para avaliação de fosfato de sitagliptina
(Universidade Federal de Santa Maria, 2010-04-16)
Sitagliptin Phosphate is an oral anti-hyperglycemic belonging to a new class of
medicine used in type 2 diabetes treatment, the dipeptidyl dipetidase -4 (DPP-4) enzyme
inhibitors. This drug besides being safe and tolerated, ...
Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...
Controle botânico, físico-químico e atividade anti-inflamatória de Glechon spathulata Benth. (Lamiaceae)
(Universidade Federal de Santa Maria, 2010-07-13)
The quality of plant-derived drugs must be ensured through tests of authenticity (organoleptic features,
macro and microscopic identification), purity and integrity (foreign matter, total ash, acid insoluble ash, loss ...
Atividade antioxidante de flavonóides e terpenóides obtidos das folhas e da casca do tronco de Scutia buxifolia Reissek
(Universidade Federal de Santa Maria, 2010-03-30)
The Rhamnaceae family is composed of some 58 genera and about 900 species. Scutia buxifolia Reissek species, popularly known as coronilha, is a local plant from South America, with a dispersion that comprise Rio Grande do ...
Detecção da resistência à oxacilina e perfil de sensibilidade de Staphylococcus coagulase negativos isolados em um hospital escola
(Universidade Federal de Santa Maria, 2010-10-29)
For many years coagulase negative Staphylococcus (CoNS), skin commensals, were regarded as mere contaminants. However, in recent decades, they emerged as important agents of nosocomial infections, particularly in ...
Caracterização de antígenos imunodominantes de Pythium insidiosum reconhecidos por anticorpos de eqüinos, coelhos e bovinos
(Universidade Federal de Santa Maria, 2010-07-26)
Oomycete Pythium insisiosum is the etiologic agent of pythiosis, chronic and granulomatous disease, which affects humans and animals in tropical and subtropical areas of the world. Due to ergosterol absence in the plasmatic ...