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Itens para a visualização no momento 11-20 of 36
Desenvolvimento e validação de metodologia para avaliação de fosfato de sitagliptina
(Universidade Federal de Santa Maria, 2010-04-16)
Sitagliptin Phosphate is an oral anti-hyperglycemic belonging to a new class of
medicine used in type 2 diabetes treatment, the dipeptidyl dipetidase -4 (DPP-4) enzyme
inhibitors. This drug besides being safe and tolerated, ...
Estudo de metodologias para avaliação do hormônio da paratireóide humano recombinante
(Universidade Federal de Santa Maria, 2013-01-31)
Human parathyroid hormone (hPTH) is a polypeptide with 84 amino acids and it is the
most important peptide regulator for calcium and phosphate ion homeostasis, maintaining
bone structure. Recombinant human parathyroid ...
Desenvolvimento de nanocápsulas contendo cetoprofeno e avaliação in vitro da citotoxicidade
(Universidade Federal de Santa Maria, 2013-08-28)
The aim of this work was to prepare, characterize and evaluate the in vitro cytotoxicity of Eudragit S100® nanocapsules (NC) containing ketoprofen. The nanostructured suspensions were prepared in triplicate by the method ...
Desenvolvimento de sistemas microparticulados planejados para a liberação oral do risedronato de sódio
(Universidade Federal de Santa Maria, 2012-08-27)
This work aimed the development of polymeric microparticles containing sodium
risedronate from Eudragit S100® (MP-EUD) and the blend, Eudragit S100® and Pullulan
(MP-EUD-PUL), through spray-drying technique. MP-EUD were ...
Avaliação de biomarcadores associados à inflamação e ao estresse oxidativo em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2013-01-28)
Changes in recent decades in morbidity and mortality of prostate cancer (CAP) is
making if a public health problem in several countries, including Brazil. Several studies
provide evidence that inflammatory processes and ...
Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...
Avaliação da atividade antibacteriana, citotóxica e nuclease química de complexos triazenidos de platina (II)
(Universidade Federal de Santa Maria, 2015-04-30)
Despite the large number of antimicrobials and anti-tumor drugs, therapeutic arsenal is limited due to the emergence of bacterial resistance mechanisms and refractoriness, besides the toxicity of certain drugs. This has ...
Análise fitoquímica, avaliação da atividade antioxidante e antimicrobiana de Solanum guaraniticum A. St.- Hil
(Universidade Federal de Santa Maria, 2013-06-14)
The Solanaceae family is one of the largest and most complex, especially the Solanum genus, with
about 1500 species. Solanum guaraniticum is a shrub found in Paraguay, Argentina and Brazil,
popularly known as jurubeba ...
Triazenos e complexos triazenidos de ouro(I) e cobre(II): atividade antileucêmica e antibacteriana in vitro
(Universidade Federal de Santa Maria, 2013-03-22)
Cancer represents one of the leading causes of death worldwide and efforts to discover more effective anticancer therapies have led to the synthesis of a wide diversity of molecular species. Furthermore, the increase of ...
Distinção entre hematogônias e blastos em pacientes portadores de leucemia linfocítica aguda de células B
(Universidade Federal de Santa Maria, 2013-12-12)
Hematogones are B-lineage lymphoid precursors cells normally found in bone marrow. The B-cell Acute Lymphocytic Leukemia (B-ALL) is a lymphocytic precursors neoplasia with consequent accumulation of immature cells called ...