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Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...
Avaliação da atividade antibacteriana, citotóxica e nuclease química de complexos triazenidos de platina (II)
(Universidade Federal de Santa Maria, 2015-04-30)
Despite the large number of antimicrobials and anti-tumor drugs, therapeutic arsenal is limited due to the emergence of bacterial resistance mechanisms and refractoriness, besides the toxicity of certain drugs. This has ...
Análise fitoquímica, avaliação da atividade antioxidante e antimicrobiana de Solanum guaraniticum A. St.- Hil
(Universidade Federal de Santa Maria, 2013-06-14)
The Solanaceae family is one of the largest and most complex, especially the Solanum genus, with
about 1500 species. Solanum guaraniticum is a shrub found in Paraguay, Argentina and Brazil,
popularly known as jurubeba ...
Triazenos e complexos triazenidos de ouro(I) e cobre(II): atividade antileucêmica e antibacteriana in vitro
(Universidade Federal de Santa Maria, 2013-03-22)
Cancer represents one of the leading causes of death worldwide and efforts to discover more effective anticancer therapies have led to the synthesis of a wide diversity of molecular species. Furthermore, the increase of ...
Distinção entre hematogônias e blastos em pacientes portadores de leucemia linfocítica aguda de células B
(Universidade Federal de Santa Maria, 2013-12-12)
Hematogones are B-lineage lymphoid precursors cells normally found in bone marrow. The B-cell Acute Lymphocytic Leukemia (B-ALL) is a lymphocytic precursors neoplasia with consequent accumulation of immature cells called ...
Desenvolvimento de micropartículas e comprimidos microparticulados contendo piperina
(Universidade Federal de Santa Maria, 2019-08-30)
Piperine is an alkaloid extracted from plants of the Piper genus, among which is the Piper nigrum species, the black pepper, widely employed in Indian cooking and traditional medicine. Moreover, piperine exhibits important ...
Desenvolvimento e validação de método por cromatografia líquida em fase reversa para avaliação de interleucina-11 humana recombinante. Correlação com o bioensaio
(Universidade Federal de Santa Maria, 2011-07-28)
Interleukin 11 (IL-11) is a multifunctional cytokine in the IL-6 type family of long-chain
helical cytokines, which modulates the proliferation, differentiation and maturation of various types of
hematopoietic cells. ...
Avaliação de potência de toxina botulínica tipo a por ensaios biológicos e método por cromatografia líquida em fase reversa
(Universidade Federal de Santa Maria, 2015-02-26)
Botulinum toxin type A (BTTA) is a polypeptide with 1296 amino acids and its used in some pathologies like hyperhidrosis and migraine, but the cosmetic area is the most important application. BTTA is produced from broth-culture ...
Avaliação do fibrinogênio como uma nova fonte para a formação in vitro de produtos proteicos de oxidação avançada
(Universidade Federal de Santa Maria, 2015-07-08)
Oxidative stress is characterized by an imbalance between the production of free radicals, particularly reactive oxygen species (ROS), and the defense capacity of the organism against these species, leading to a progressive ...
Reposicionamento e avaliação da atividade antibacteriana e de clivagem do DNA plasmidial in vitro dos não antibióticos Anlodipino e Valsartana
(Universidade Federal de Santa Maria, 2019-12-19)
Infections caused by multiresistant microrganisms have increased considerably in recent years,
reaching approximately one fifth of worldwide mortality, becoming a public health problem. Another
worrying factor is the ...