Buscar
Itens para a visualização no momento 31-40 of 331
Desenvolvimento de nanocápsulas contendo cetoprofeno e avaliação in vitro da citotoxicidade
(Universidade Federal de Santa Maria, 2013-08-28)
The aim of this work was to prepare, characterize and evaluate the in vitro cytotoxicity of Eudragit S100® nanocapsules (NC) containing ketoprofen. The nanostructured suspensions were prepared in triplicate by the method ...
Desenvolvimento de sistemas microparticulados planejados para a liberação oral do risedronato de sódio
(Universidade Federal de Santa Maria, 2012-08-27)
This work aimed the development of polymeric microparticles containing sodium
risedronate from Eudragit S100® (MP-EUD) and the blend, Eudragit S100® and Pullulan
(MP-EUD-PUL), through spray-drying technique. MP-EUD were ...
Determinação de antidepressivos tricíclicos em sangue total por cromatografia líquida com detector de arranjo de diodos empregando microextração líquido-líquido dispersiva
(Universidade Federal de Santa Maria, 2021-07-21)
Psychoactive drugs are the main agents involved in cases of intoxication according to the Toxicological Information Center of Rio Grande do Sul (CIT-RS) and the National Toxic-Pharmacological Information System (Sinitox). ...
Avaliação de biomarcadores associados à inflamação e ao estresse oxidativo em pacientes com câncer de próstata
(Universidade Federal de Santa Maria, 2013-01-28)
Changes in recent decades in morbidity and mortality of prostate cancer (CAP) is
making if a public health problem in several countries, including Brazil. Several studies
provide evidence that inflammatory processes and ...
Avaliação da ligação da albumina humana ao níquel e sua potencial aplicação na detecção da isquemia cardíaca
(Universidade Federal de Santa Maria, 2010-07-16)
Acute coronary syndrome (ACS) is characterized by the occurrence of a set of signs and
symptoms that are related to myocardial ischemia. Unstable angina (UA) and acute
myocardial infarction with ST segment elevation ...
Avaliação da atividade antibacteriana, citotóxica e nuclease química de complexos triazenidos de platina (II)
(Universidade Federal de Santa Maria, 2015-04-30)
Despite the large number of antimicrobials and anti-tumor drugs, therapeutic arsenal is limited due to the emergence of bacterial resistance mechanisms and refractoriness, besides the toxicity of certain drugs. This has ...
Análise fitoquímica, avaliação da atividade antioxidante e antimicrobiana de Solanum guaraniticum A. St.- Hil
(Universidade Federal de Santa Maria, 2013-06-14)
The Solanaceae family is one of the largest and most complex, especially the Solanum genus, with
about 1500 species. Solanum guaraniticum is a shrub found in Paraguay, Argentina and Brazil,
popularly known as jurubeba ...
Triazenos e complexos triazenidos de ouro(I) e cobre(II): atividade antileucêmica e antibacteriana in vitro
(Universidade Federal de Santa Maria, 2013-03-22)
Cancer represents one of the leading causes of death worldwide and efforts to discover more effective anticancer therapies have led to the synthesis of a wide diversity of molecular species. Furthermore, the increase of ...
Distinção entre hematogônias e blastos em pacientes portadores de leucemia linfocítica aguda de células B
(Universidade Federal de Santa Maria, 2013-12-12)
Hematogones are B-lineage lymphoid precursors cells normally found in bone marrow. The B-cell Acute Lymphocytic Leukemia (B-ALL) is a lymphocytic precursors neoplasia with consequent accumulation of immature cells called ...
Desenvolvimento de micropartículas e comprimidos microparticulados contendo piperina
(Universidade Federal de Santa Maria, 2019-08-30)
Piperine is an alkaloid extracted from plants of the Piper genus, among which is the Piper nigrum species, the black pepper, widely employed in Indian cooking and traditional medicine. Moreover, piperine exhibits important ...