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Itens para a visualização no momento 121-130 of 191
Envolvimento de fatores oxidativos e inflamatórios sobre a resistência ao tratamento com fluoxetina em um modelo de depressão em camundongos
(Universidade Federal de Santa Maria, 2021-10-27)
Major depression (DM) is among the most disabling mental disorders in the world. According to the World Health Organization (WHO), more than 300 million people are affected by DM. The disorder is characterized by a set of ...
Efeito do beta-cariofileno na suscetibilidade hepática e renal à aflatoxina B1 em parâmetros bioquímicos, oxidativos e moleculares em ratos
(Universidade Federal de Santa Maria, 2021-08-13)
Aflatoxin B1 (AFB1) is a mycotoxin produced manly by Aspergillus flavus and Aspergillus
parasiticus fungi. Among the existing mycotoxins, AFB1 has been the most studied due to its
high toxigenic potential. Exposure to ...
Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
(Universidade Federal de Santa Maria, 2018-05-29)
This study aimed to characterize the essential oils of Alpinia speciosa (EOAS), Eremanthus erythropappus (EOEE), Schinus lentiscifolius (EOSL), Hesperozygis ringens (EOHR) and Ocimum americanum (EOOA), and to investigate ...
Alterações bioquímicas e estresse oxidativo associados ao hipotireoidismo
(Universidade Federal de Santa Maria, 2010-03-18)
Overt hypothyroidism is characterized by decreased of thyroid hormones synthesis,
with elevation of thyroid-stimulating hormone (TSH). It s a common disorder in
population with highest prevalence in women and with aging. ...
Depressão: aspectos fisiopatológicos e o efeito tipo-antidepressivo da apocinina
(Universidade Federal de Santa Maria, 2020-02-17)
Depression is considered a public health challenge around the world. According to the World Health Organization, more than 300 million people (approximately 6% of the world population) are affected by this disorder. ...
Envolvimento do canal TRPA1 nos comportamentos do tipo depressivo e ansioso em um modelo de esclerose múltipla progressiva em camundongos
(Universidade Federal de Santa Maria, 2020-09-25)
Background and Purpose: Progressive multiple sclerosis (PMS) is a neurological disease associated with the development of depression and anxiety, and treatments available are unsatisfactory. The transient potential receptor ...
Efeito modulatório in vitro da quetiapina não-metabolizada na citotoxicidade e ativação inflamatória de células brancas e na formação de armadilhas extracelulares de neutrófilos
(Universidade Federal de Santa Maria, 2020-02-19)
Quetiapine (QUE) is a highly complex drug that, due to its different forms of interaction with receptors, has great clinical applicability. Although widely used, QUE brings with it a range of side effects that include, in ...
Beta-cariofileno atenua dano cognitivo induzido pela exposição ao aspartame em ratos pela modulação da atividade da acetilcolinesterase e da Via BDNF/TrKB
(Universidade Federal de Santa Maria, 2021-08-26)
Aspartame (ASP) is a widely used as a tabletop sweetener and sucrose substitute in many
food matrices. However, several studies have reported that exposure to ASP can damage
biological tissues, such as the central nervous ...
Efeitos benéficos do ácido rosmarínico em modelos de atividade epileptiforme in vivo e in vitro induzidos por pilocarpina
(Universidade Federal de Santa Maria, 2021-12-17)
Epilepsy is a chronic neurological condition marked by the occurrence of epileptic seizures that cause enormous damage to the quality of life of affected patients. Thus, understanding the molecular bases responsible for ...
O conteúdo dietético dos ácidos graxos modifica parâmetros de memória em ratos: estudo comparativo entre uma dieta baseada no mediterrâneo versus dietas ocidentais
(Universidade Federal de Santa Maria, 2018-02-08)
Population aging associated with altered eating habits has been increasing the incidence of cognitive impairment and neurodegenerative diseases, including Alzheimer's disease (AD), which is a serious public health problem ...