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Aumento da suscetibilidade ao pentilenotetrazol após a sobrevivência de um quadro de malária cerebral em camundongos
(Universidade Federal de Santa Maria, 2017-07-10)
Malaria is considered a neglected disease and public health problem, affecting more than 200 million people worldwide. Plasmodium falciparum, one of the four human parasitic species, is responsible for the development of ...
Associação da via inflamatória e apoptótica na patofisiologia do acidente vascular encefálico tardio: relação com a dislipidemia
(Universidade Federal de Santa Maria, 2015-01-22)
Stroke occurs when blood flow to the brain is interrupted by an embolic or thrombotic occlusion of a cerebral artery (ischemic stroke) or by bleeding from a ruptured blood vessel (hemorrhagic stroke). Oxidative stress and ...
Efeito farmacogenético do polimorfismo Ala16Val do gene da MnSOD na resposta de pacientes hipercolesterolêmicos a rosuvastatina
(Universidade Federal de Santa Maria, 2015-02-27)
Rosuvastatin is used as a drug of first choice in treating hypercholesterolemia due to
competitive inhibition of HMG-CoA reductase enzyme which converts HMG-CoA to
mevalonic acid which is the rate-limiting step in ...
Atividade imunomoduladora de células dendríticas pulsadas com antígenos de Pythium insidiosum sobre a resposta celular in vitro
(Universidade Federal de Santa Maria, 2016-03-15)
Pythiosis is a severe disease caused by the Oomycete Pythium insidiosum which can affect
animals and humans. If not diagnosed and immediately treated, pythiosis can lead the affected
host to death. Pythiosis treatment ...
Avaliação dos efeitos de um campo magnético pulsado sobre a cicatrização cutânea e biomarcadores oxidativos em ratos wistar
(Universidade Federal de Santa Maria, 2015-08-14)
The surgical postoperative period requires rapid, effective and good-quality wound repair. For a better cicatrization process alternatives have been sought to assist wound repair and improve the appearance of scarred region. ...
Terapia de emissão de luz por diodo induz analgesia em modelos de nocicepção em camundongos: análise do mecanismo de ação
(Universidade Federal de Santa Maria, 2015-09-04)
The LEDT is a fairly recent category of phototherapy and there is evidence that accelerates wound healing, reduce inflammation and painful. However, there are few scientific studies on the action mechanisms of LEDT in pain ...
Efeitos do uso do acetato de leuprolide nas caraterísticas reprodutivas de roedores submetidos ao tratamento com testosterona propionato pré e pós-natal
(Universidade Federal de Santa Maria, 2016-07-30)
Androgen excess induces in female rats reproductive and metabolic disturbances that are similar to polycystic ovary syndrome in women. In these animals, the degree of changes may vary according to the timeline intervention, ...
Ação da rutina e oxitetraciclina sobre os parâmetros bioquímicos e oxidativos em tecidos de Rhamdia quelen
(Universidade Federal de Santa Maria, 2017-03-23)
Fish farming conditions can lead to stress situations, contributing to the occurrence of infectious diseases, considered a great challenge for the productive success of this activity. Thus, antibiotics have been used for ...
Efeito do ácido rosmarínico sobre as crises epilépticas e alterações comportamentais em diferentes modelos experimentais de epilepsia
(Universidade Federal de Santa Maria, 2016-03-01)
Epilepsy is a chronic neurological disease characterized by recurrent seizures. Current anticonvulsant
drugs are ineffective in nearly one third of patients and may cause significant adverse effects.
Rosmarinic acid is ...
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
(Universidade Federal de Santa Maria, 2016-03-02)
Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of
fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore,
strategies for early diagnosis ...