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Ação protetora da Carya illinoensis sobre a toxicidade induzida por ciclofosfamida em ratos
(Universidade Federal de Santa Maria, 2010-01-29)
Cyclophosphamide (CP) is an alkylating agent widely used in anticancer and immunosuppression therapy. Like other chemotherapies, this drug can induce damage in healthy tissues, generating multiple organ toxicity. The study ...
Adição do óleo essencial de Lippia alba (Mill) N. E. Brown na dieta do jundiá: análise do crescimento e da resposta antioxidante
(Universidade Federal de Santa Maria, 2013-02-06)
Fish become more susceptible to stress and, consequently, to the onset of disease with the intensification of rearing. In an attempt to minimize this problem, farmers use agrochemicals that, besides harming the environment, ...
Efeitos benéficos do extrato das cascas de noz pecã (Carya illinoensis) sobre parâmetros bioquímicos e comportamentais de camundongos expostos ao fumo passivo
(Universidade Federal de Santa Maria, 2011-01-28)
Smoking is the second major reason of death worldwide, amounting 5 millions
of deaths annually. The adverse effects of cigarette smoking are not limited to active
smokers, but also to passive smokers, which comprise one ...
Influência do exercício físico sobre parâmetros de comportamento e estresse oxidativo em modelo animal de discinesia tardia
(Universidade Federal de Santa Maria, 2008-03-07)
Regular practice of physical activity promotes beneficial effects to the body. However, excessive duration and intensity of exercise may surpass individual tolerance to
exercise, generating oxidative stress (OS). Studies ...
Estudo toxicológico comparativo referente ao haloperidol na sua forma livre e nanoencapsulada
(Universidade Federal de Santa Maria, 2015-08-14)
The association of haloperidol (HP) with polymeric nanocapsules causes a significant improve in therapeutic efficacy prolongs the drug time of action and reduces motor side effects in rats. However, in view of the HP ...
Quantificação de α-tocoferol, retinol e carotenóides e seus possíveis efeitos sobre a peroxidação lipídica em trabalhadores expostos a solventes
(Universidade Federal de Santa Maria, 2011-02-18)
Oxidative stress is a process characterized by the antioxidant defense system
decrease and/or an excessive reactive species (RS) production. RS are substances
capable of attacking proteins, lipids and DNA. The oxidative ...
Influência do polimorfismo Ala16Val do gene da enzima superóxido dismutase (SOD2) no efeito antioxidante in vitro do citrato de clomifeno
(Universidade Federal de Santa Maria, 2011-08-16)
To investigate the in vitro antioxidant properties of the ovulation induction drug,
Citrate clomiphene (CC), and to access whether its effects are influenced by the
Ala16Val polymorphism in the SOD2 gene, which encodes ...
Frutose-1,6-bisfosfato e N-acetilcisteína atenuam a formação de produtos proteicos de oxidação avançada, uma nova classe de mediadores inflamatórios, in vitro
(Universidade Federal de Santa Maria, 2012-09-19)
The assessment of biomarkers of reactions involving reactive oxygen species have the
potential not only to determine the extent of oxidative damage, but also to predict the
effectiveness of therapeutic strategies aimed ...
Efeito da administração oral de aflatoxina B1 nas convulsões induzidas em ratos
(Universidade Federal de Santa Maria, 2014-08-14)
Aflatoxins are produced by Aspergillus flavus fungi, mainly A. parasiticus and A. nomius. Aflatoxin B1 (AFB1) is the most common and highly toxic mycotoxin, presents carcinogenic, mutagenic and teratogenic effects. This ...
Efeito do óleo essencial de lippia alba nos parâmetros oxidativos do jundiá (Rhamdia quelen) exposto a diferentes concentrações de oxigênio
(Universidade Federal de Santa Maria, 2009-09-01)
Juvenile silver fish (Rhamdia quelen) were exposed to the essential oil of
Lippia alba (L. alba) and transported in plastic bags for different periods (5, 6 and 7
h) yielding final different oxygen levels. The biomarkers ...