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Efeito in vitro do extrato de Solanum sessiliflorum: atividade antioxidante e antitumoral (MCF-7 e HT29)
(Universidade Federal de Santa Maria, 2015-11-05)
Epidemiological studies have suggested that intake of fruits and vegetables act in the prevention of several diseases such as cancer and cardiovascular diseases. This can be explained by these bioactive compounds are present ...
Avaliação do potencial antioxidante e antibacteriano de Anacardium microcarpum e sua toxicidade em diferentes modelos biológicos in vitro
(Universidade Federal de Santa Maria, 2015-09-11)
Oxidative stress reflects an imbalance between the systemic manifestation of reactive species and a biological system s ability to readily detoxify the reactive intermediates or to repair the resulting damage. This condition ...
Consumo de mel fornece proteção contra alterações motoras e moleculares induzidas por hipóxia/reperfusão em Drosophila melanogaster
(Universidade Federal de Santa Maria, 2017-02-14)
Honey is a complex product produced by honeybees from nectar, being widely used for its sweetening properties, as well as for its benefits to human health. Honey presents anti-inflammatory, hypoglycemic and antioxidant ...
Propriedades antinociceptivas e antioxidantes do disseleneto de bis(fenilimidazoselenazolila) em roedores
(Universidade Federal de Santa Maria, 2016-11-07)
The current available drugs for treatment of disorders related to pain and inflammation present several adverse effects, then the investigation for novel molecules are required. It is known that organoselenium compounds ...
Propriedades de proteção gastrointestinal da Rosmarinus officinalis l. em associação a testes microbiológicos e antioxidantes in vitro e ex vivo
(Universidade Federal de Santa Maria, 2016-03-18)
The elevate production of reactive species over physiological levels and associated to pathogenic bacteria could
represent a high risk for many diseases. The high levels of oxidative stress and inflammation can be present ...
Síntese e atividades antioxidante e antitumoral de 5´-arilseleno azidotimidina
(Universidade Federal de Santa Maria, 2012-03-30)
The synthesis of compounds that use a nucleoside as the base structure, has an intense field application. Among these compounds, the most known nowadays is azydothymidine or zidovudine, a drug which was first synthesized ...
Avaliação de marcadores bioquímicos, de estresse oxidativo e do efeito antioxidante da quercetina no hipotireoidismo
(Universidade Federal de Santa Maria, 2014-03-28)
Hypothyroidism is characterized by a disorder resulting from deficiency of
thyroid hormones and is related to lipid metabolism dysfunction and cardiovascular
diseases development risk. However, these changes in hypothyroidism ...
Efeitos dos compostos de selênio e zinco nas lesões gastrointestinais induzidas por etanol em ratos
(Universidade Federal de Santa Maria, 2012-03-30)
Gastric ulcer is a world widespread illness that affectes a great number of people and it is correlated to life style, food intake, alcohol and smoke in association or not to stress behavior. The lesions are in association ...
Disseleneto de p-metoxi fenila atenua o prejuízo cognitivo e a injúria cerebral em um modelo da doença de Alzheimer em roedores
(Universidade Federal de Santa Maria, 2012-09-17)
Alzheimer s disease (AD) is a progressive neurodegenerative disorder, mainly characterized by memory and intellectual capacity loss. AD is characterized by deposition of amyloid-β peptide, neurofibrillary tangles, ...
Avaliação da atividade antioxidante de diferentes classes de compostos contra a oxidação de lipoproteínas de baixa densidade
(Universidade Federal de Santa Maria, 2011-10-04)
Abnormalities of lipid metabolism often lead to pathologic lipid accumulation in the
vessel wall, oxidative and chronic inflammatory sequelae and the formation of atherosclerotic
lesions, ultimately leading to clinical ...