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Avaliação fitoquímica, antioxidante e anti-inflamatória de Solanum corymbiflorum
(Universidade Federal de Santa Maria, 2017-02-20)
The plants have compounds that are related to different biological activities. Among these
compounds, stand out the phenolic compounds which are capable of eliminate free radicals,
and therefore, are involved in several ...
Atividade antimicrobiana, antibiofilme, cito e genotóxica do S- (3,4-diclorobenzil) isotioureia (A22)
(Universidade Federal de Santa Maria, 2017-08-25)
Biofilm formation causes great public health concern due to the low response to antimicrobial
treatments and the colonization of surfaces such as prostheses and catheters. Pathogenic
microorganisms such as Pseudomonas ...
Desenvolvimento e avaliação do potencial citotóxico de complexos de inclusão dronedarona/ciclodextrinas
(Universidade Federal de Santa Maria, 2017-09-06)
Dronedarone is a new antiarrhythmic agent, analogue of amiodarone. Dronedarone was approved for the maintenance of the sinus rhythmic in adult patients with atrial fibrillation. Dronedarone show bioavailability problems ...
Composição química, atividade anti-inflamatória e toxicidade aguda e subaguda de Verbena litoralis kunth
(Universidade Federal de Santa Maria, 2017-12-20)
Verbena litoralis Kunth belongs to the Verbenaceae family, which is native to South America and can be found in tropical and subtropical regions, especially in the temperate regions of the Southern Hemisphere. It is popularly ...
Vaccinium ashei reade: da análise fitoquímica das folhas ao desenvolvimento de nanopartículas e avaliação das atividades antioxidante e antidepressiva
(Universidade Federal de Santa Maria, 2017-12-01)
The Vaccinium ashei Reade, known as blueberry, production and commercialization has become each time more popular due to its nutritional and pharmacological properties related to its consumption. Despite having a commercial ...
Avaliação da potência do hormônio da paratireóide humano recombinante por bioensaio, métodos cromatográficos e eletroforético
(Universidade Federal de Santa Maria, 2017-05-24)
The human parathyroid hormone (hPTH) is a polypeptide secreted by the parathyroid glands that is essential for the maintenance of the calcium ion homeostasis in the blood. The recombinant DNA technology has enabled the ...
Desenvolvimento e avaliação biológica de hidrogel contendo nanocápsulas de óleo de romã e silibinina para o tratamento de danos inflamatórios cutâneos causados pela radiação ultravioleta
(Universidade Federal de Santa Maria, 2017-07-26)
Silibinin (SB) is a flavonoid extracted from the plant Silybum marianum that has been studied as an active substance to protect the skin against damage ultraviolet-induced. Its limited solubility and bioavailability impairs ...
Atividade das enzimas que degradam nucleotídeos e nucleosídeo da adenina em leucemia linfoblástica aguda B derivada
(Universidade Federal de Santa Maria, 2017-09-01)
B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a neoplasm characterized by an anomalous clonal proliferation of B lymphoid precursor cells and predominance in pediatric patients. BCP-ALL promotes the deregulation ...
Investigação da resistência bacteriana e avaliação de metodologias em isolados clínicos de Pseudomonas aeruginosa e Acinetobacter spp. de diferentes anos em um hospital universitário
(Universidade Federal de Santa Maria, 2017-04-28)
Pseudomonas aeruginosa and Acinetobacter spp. are microorganisms worldwide reported as pathogens of high prevalence in the etiology of nosocomial infections; they are opportunistic and have clinical importance in Health ...
Caracterização dos SCCmec e produção de biofilme em Staphylococcus aureus no Hospital Universitário de Santa Maria
(Universidade Federal de Santa Maria, 2017-08-11)
Staphylococcus aureus, in particular those resistant to methicillin (MRSA), are reported worldwide as pathogens of high prevalence in the etiology of infections. Its versatility as an important etiological agent results ...