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Resistência de biofilmes formados por micobactérias de crescimento rápido frente a antimicrobianos
(Universidade Federal de Santa Maria, 2018-03-28)
Rapidly growing mycobacteria (RGM) are opportunistic pathogens that produce diseases in a variety of clinical settings. The environmental nature of RGM and their ability to assemble biofilms on different surfaces play a ...
Nanocapsules of the tucumã oil (Astrocaryum vulgare Mart): preparation, characterization, safety evaluation in vitro and in vivo and antitumoral effectiveness in vitro
(Universidade Federal de Santa Maria, 2019-08-23)
Breast cancer is a disease of great molecular complexity and its incidence grows every year.
By 2019 approximately sixty thousand new cases are expected in Brazil, as it generates
concern mainly for women. In view of ...
Desenvolvimento de formas farmacêuticas sólidas e semissólidas contendo piperina associada a nanocarreadores
(Universidade Federal de Santa Maria, 2018-08-17)
The possibility of associating natural actives with nanostructured systems appears as a less invasive
treatment option for the organism. This is because, nanoparticles are able to control the release and
attenuate the ...
Desenvolvimento e avaliação biológica de hidrogel contendo nanocápsulas de óleo de romã e silibinina para o tratamento de danos inflamatórios cutâneos causados pela radiação ultravioleta
(Universidade Federal de Santa Maria, 2017-07-26)
Silibinin (SB) is a flavonoid extracted from the plant Silybum marianum that has been studied as an active substance to protect the skin against damage ultraviolet-induced. Its limited solubility and bioavailability impairs ...
Atividade das enzimas purinérgicas e o uso de nanocápsulas de óleo de romã e silibinina no melanoma cutâneo
(Universidade Federal de Santa Maria, 2022-10-31)
Cancer is a multifactorial disease resulting from mutations in specific genes that cause cell
hyperproliferation. Currently, the most prevalent type of cancer is skin cancer, and its most
aggressive subtype is melanoma. ...
Desenvolvimento de nanocápsulas peguiladas de risperidona em diferentes óleos: avaliação in vitro e in vivo
(Universidade Federal de Santa Maria, 2016-08-31)
This study aims to develop PEGylated nanocapsules containing Risperidone (RIS) in different oils and evaluate its performance in vivo and in vitro. The oils utilized for the results comparison were sesame (Ge), linseed ...
Formulações nanotecnologicas contendo ácido ferúlico: modelagem in silico, desenvolvimento e avaliação biológica
(Universidade Federal de Santa Maria, 2024-01-31)
Natural molecules, such as ferulic acid (FA), are increasingly under investigation due to
their properties, including antioxidant, neuroprotective, anti-inflammatory, photoprotective,
hepatoprotective, antimicrobial, ...
Avaliação tecnológica e biológica de formulações promissoras para o tratamento da malária
(Universidade Federal de Santa Maria, 2024-04-30)
Malaria is an inflammatory disease that affects millions of people worldwide. Our research group has been devoted to the development and evaluation of nanocapsules containing antimalarial drugs for disease treatment, ...